Abstract Background A synergistic inhibiting effect on glioblastoma cell proliferation was reported for the combination of TTFields and radiotherapy. Based these preclinical findings, we performed phase I/II PriCoTTF trial in adult nGBM patients to investigate safety efficacy therapy initiated prior concomitant radiochemotherapy. MATERIAL AND METHODS In this trial, following surgery continued t...

Combined radiochemotherapy is the recommended standard postoperative therapy for patients with stage II and III rectal cancer in the USA and in Germany. During thelast decade, substantial progress has been made in treatment modalities: surgical management currently includes a broad spectrum of operative procedures ranging from radical operations such as abdominoperineal resections to innovative...

A histopathological survey of surgical materials from 143 patients with rectal carcinoma subjected to chemotherapy and low-dose radiotherapy with tegafur and bleomycin was carried out. The chemotherapy combined with radiotherapy brought about better results than chemotherapy alone. In 4 of the 58 patients treated with radiochemotherapy, no cancer cells could be found in surgical specimens. Exfo...

Recurrent malignancy at esophagojejunal anastomosis represents an incurable stage of disease. Treatment options are limited. Surgery presents a high rate of morbidity and mortality and frequently fails to alleviate symptoms. Radiochemotherapy relieves dysphagia slowly and offers disappointing clinical results. The use of Self Expanding Metallic Stent (SEMS) has shown to be effective, safe and o...