Abstract While magnetic resonance imaging (MRI) is the predominant modality for glioblastoma (GBM), pre-clinical MRI scanner availability limited. As CT more widely available and cost-effective, this study aimed to 1) establish preclinical-GBM CT-radiomic workflows, 2) identify whether CE-CT could detect murine orthotopic GBM tumours on two instruments [TRIUMPHX-O-CT; IVISSPECTRUM-CT], 3) asses...