This study examined the contribution of delayed apoptosis of bronchial mucous cells to mucus accumulation in equine recurrent airway obstruction (RAO). In pilot studies, Bcl-2, an apoptosis inhibitor, was detected in airway mucous cells of RAO-affected horses in remission and during acute disease, when most mucus was secreted. To study whether delayed apoptosis results in an increase in the num...

Equine recurrent airway obstruction (RAO) has been used as a naturally occurring model of human asthma. However, it is unknown whether there is an early-phase response in RAO. The aim of this study was to determine whether exposure to organic dust induces immediate changes in lung function in RAO-affected horses, which could be mediated by airway mast cells. Six RAO-affected horses in remission...

Metaheuristic optimisation algorithms have been increasingly used because of their superior ability to find globally optimal solutions. Theoretically, these are very powerful and can be applied in all types problems. However, reality, performance depends on the characteristics each problem class. In addition, complexity an algorithm is important factor affecting its application specific design ...

To evaluate the functional status of neuronal α2-adrenoceptors (ARs) and β2-ARs on ACh release in horses with recurrent airway obstruction (RAO), we examined the effects of the physiological agonists epinephrine (Epi) and norepinephrine (NE) and the β2-agonists RR- and RR/ SS-formoterol on ACh release from airway cholinergic nerves of horses with RAO. Because SS-formoterol, a distomer of the β2...

INTRODUCTION: Rotational acetabular osteotomy (RAO) has been recognized as an useful procedure, especially for early stage of osteoarthritis of the hip, with satisfactory intermediate and long-term results. In RAO, it is important to rotate the acetabular roof sufficiently, contributing to improvement of the acetabular roof coverage. On the other hand, femoroacetabular impingement due to acetab...

The effects of some synthetic sweeteners on the rheological and physical properties of guar gum in dilute solutions were investigated.Measurements include the determination of intrinsic viscosity and the particle size, surface weighted mean [D3, 2], volume weighted mean [D4,3] and specificsurface area ofguar gum andsyntheticsweeteners mixtures. T...

BACKGROUND Multiple hypersensitivities (MHS) have been described in humans, cats, and dogs, but not horses. HYPOTHESES Horses suffering from recurrent airway obstruction (RAO), insect bite hypersensitivity (IBH), or urticaria (URT) will have an increased risk of also being affected by another one of these hypersensitivities. This predisposition for MHS also will be associated with decreased s...

We use Taiwanese national health insurance research database (NHIRD) to investigate whether thrombolism (carotid artery disease (CAD) as a surrogate) or embolism (atrial fibrillation (AF) as a surrogate) plays roles in later retinal artery occlusion (RAO) development and examine their relative weights. The relative risks of RAO between AF and CAD patients and controls were compared by estimatin...

PURPOSE The aim of this study was to investigate the mean platelet volume (MPV) of patients with retinal artery occlusion (RAO). METHODS Thirty-seven patients diagnosed with RAO and 32 control subjects were included in this retrospective study. Retinal artery occlusion was diagnosed on the basis of clinical examination and fundus fluorescein angiography. All participants underwent complete oc...

All the Dr D. L. N. Murti Rao Orators so far have been persons who knew Dr D.L.N. Murti Rao personally. Some like Professor N. N. Wig, Professor A. Venkoba Rao and Professor A. Verghcse had been his students. Others like Professor K. C. Dube and Col. Kirpal Singh knew him in course of their professional interactions. I am possibly the first Dr D. L. N. Murti Rao Orator who was not fortunate eno...