Millettiae speciosae Champ. Leguminosae (MSC), is a well-known Chinese herb traditionally used as food material and medicine for enhancing physical strength. Our preliminary study found that the aqueous extract of this herb (MSE) had an anti-fatigue effect. In this paper, we further separated MSE into total polysaccharides (MSP) and supernatant (MSS) by alcohol precipitation, and explored which...

Leishmania chagasi is the causative agent of visceral leishmaniasis in South America. The most abundant glycoprotein on the surface of L. chagasi promastigotes is the glycosylphosphatidylinositol (GPI) anchored protease MSP (major surface protease), also called GP63. MSP is encoded by more than 18 tandem MSP genes on a single chromosome. MSP genes are classified according to unique sequences at...

The Plasmodium falciparum malaria parasite is the causative agent of malaria tropica. Merozoites, one of the extracellular developmental stages of this parasite, expose at their surface the merozoite surface protein-1 complex (MSP-1), which results from the proteolytic processing of a 190-200 kDa precursor. MSP-1 is highly immunogenic in humans and numerous studies suggest that this protein is ...

ownloade kground: rs10993994, a single nucleotide polymorphism (SNP) at the genetic locus encoding βeminoprotein (β-MSP), is associated with both prostate cancer risk and levels of blood prostate-specific n (PSA), a biomarker used in prostate cancer screening. Therefore, we wished to determine the assobetween SNPs at MSMB, the gene encoding β-MSP, and the levels of prostate-produced biomarkers ...

BACKGROUND As highlighted in recent reports published by the Physician-Scientist Workforce Working Group at the National Institutes of Health, the percentage of physicians conducting research has declined over the past decade. Various programs have been put in place to support and develop current medical student interest in research to alleviate this shortage, including The Vanderbilt Universit...

Introduction: Quality and knowledge-based human resources are the most important competitive advantage and the scarcest source in today's knowledge-based economy. Hence, the development of the capabilities, expertise, and commitment of well-trained employees is considered the most important management challenge in our time. The present study was conducted to investigate the role of Management S...

Infants born in areas of stable malaria transmission are relatively protected against severe morbidity and high density Plasmodium falciparum blood-stage infection. This protection may involve prenatal sensitization and immunologic reactivity to malaria surface ligands that participate in invasion of red cells. We examined cord blood T and B cell immunity to P. falciparum merozoite surface prot...

For de novo pattern mining in genomic sequences, the main issues are constructing pattern definition model (PDM) and mining sequence patterns (MSP). The representations of PDMs and the discovery of patterns are functionally dependent; the performances thus depend on the adopted PDMs. The popular PDMs provide only descriptive patterns; they lack multifaceted considerations. Many of existing MSP ...

The cost of expanding health insurance coverage increases when people who would otherwise purchase insurance obtain public coverage. This paper investigates the effects of one of the first efforts to target insurance benefits to the most needy, the 1982 medicare as secondary payer (MSP) provisions. We find strong evidence of low compliance with the MSP both in terms of medical bill payments (pa...