Aberrant immune responses and chronic inflammation can impose significant health risks promote premature aging. Pro-inflammatory are largely mediated via reactive oxygen species (ROS) reduction–oxidation reactions. A pivotal role in maintaining cellular redox homeostasis the proper control of redox-sensitive signaling belongs to a family antioxidant redox-regulating thiol-related peroxidases de...

As alterations of the redox homeostasis lie at the root of many pathophysiological processes in human health, redox proteomics holds the promise to shed further light on fundamental biological processes. In this review, the mechanisms of reactive oxygen species (ROS) and reactive nitrogen species (RNS) production are reviewed, mainly addressing those chemical phenomena which have already been a...

Redox systems are key players in vascular health. A shift in redox homeostasis-that results in an imbalance between reactive oxygen species (ROS) generation and endogenous antioxidant defenses has the potential to create a state of oxidative stress that subsequently plays a role in the pathogenesis of a number of diseases, including those of the cardiovascular and metabolic system. Statins, whi...

Plastids are organelles present in photosynthetic and nonphotosynthetic plant tissues. While it is well known that thioredoxin-dependent redox regulation is essential for leaf chloroplast function, little is known of the redox regulation in plastids of nonphotosynthetic tissues, which cannot use light as a direct source of reducing power. Thus, the question remains whether redox regulation oper...

*Correspondence: Dhriti Kapoor, Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar-Punjab, 143005 Amritsar, India e-mail: [email protected] Contemporaneous presence of both oxidized and reduced forms of electron carriers is mandatory in efficient flux by plant electron transport cascades. This requirement is considered as redox poising that involves the movement of...