electrode potential of 2-(2,3-dihydroxy phenyl)-1,3-dithiane (dpd) was investigated by means of cyclic voltammetry (cv) at various potential scan rates. the calculated value was compared with the experimental value obtained by cyclic voltammetry (cv). all experiments were done in aqueous phosphate buffer solutions at different phs. the experimental redox potential of dpd was obtained to be 0.75...

BACKGROUND We examined the cardiovascular risk of abatacept compared with tumor necrosis factor (TNF) inhibitors in patients with rheumatoid arthritis with and without diabetes mellitus (DM). METHODS AND RESULTS We conducted a cohort study of patients with rheumatoid arthritis who newly started abatacept or TNF inhibitors using claims data from Medicare and MarketScan. The primary outcome was...

INTRODUCTION Analyses of efficacy and tolerability of pharmacologic interventions are based on clinical trials that often include predominately white populations, in part because of challenges associated with recruitment and retention of racial/ethnically diverse study populations. Using real-world electronic health record (EHR) data, we sought to evaluate the tolerability and effectiveness of ...

WHAT IS KNOWN AND OBJECTIVE Pharmacy claims are commonly used to assess medication adherence. It is unclear how different approaches to handling hospitalizations compare to the gold standard of using outpatient and inpatient drug data. This study aimed to compare the impact of different approaches to handling hospitalizations on medication adherence estimation in administrative claims data. M...

In the vast majority of atom transfer radical polymerizations, alkyl bromides or chlorides are commonly employed as initiators. Herein, iodides demonstrated ATRP

An efficient strategy for the synthesis of monoamine end-functionalized living polymers using ringopening metathesis polymerization with ruthenium initiators is reported. A new end-capping agent for this purpose was synthesized, and its efficiency for end-functionalization was evaluated using two common ruthenium-based initiators. Finally, terminal cross-metathesis was also explored as another ...

A two-photon polymerization initiator is a kind of nonlinear optical material. With the demand for more efficient initiators in additive manufacturing, there are and related studies. In this paper, four conjugate-extended with different alkane chain lengths were designed synthesized, single-photon, two-photon, photodegradation experiments carried out. Additive manufacturing illustrated that mol...

INTRODUCTION In many resource-limited settings, combination antiretroviral therapy (cART) failure is diagnosed clinically or immunologically. As such, there is a high likelihood that patients may stay on a virologically failing regimen for a substantial period of time. Here, we compared the long-term impact of initiating non-nucleoside reverse transcriptase inhibitor (NNRTI)- versus boosted pro...