PURPOSE To determine the efficacy of freeze-dried amniotic membrane (AM) for reconstruction of the ocular surface in rabbit eyes. METHODS The sterilized, freeze-dried amniotic membrane (lyophilized or FD-AM) is a preservative method that uses the drying by freezing process to maintain the AM well preserved for a long time even at room temperature. This paper is an experimental animal interven...

UNLABELLED  Introduction. Ulcers are one of the most frequent diseases af- fecting the oral cavity. The aim of this study was to assess the effects of omega-3 fatty acid (topical and systemic) on oral mucosa wound healing in rats. METHODS AND MATERIALS In this study, adult male rats in 5 groups (n = 16 per group) were used (L: local, S: systemic, LB: local blank, SB: systemic blank, and...

The stimulatory effect of recombinant basic fibroblast growth factor (bFGF) on wound healing was assessed using healing-impaired (db/db) mice. Full-thickness wounds were made in female diabetic C57BL/Ksj AM mice, and their normal (db/+) littermates with a punch biopsy instrument . Recombinant bFGF was applied locally to the open wound once a day. The mice were later killed and histological sect...

Burn-related morbidity and mortality are usually caused by secondary infection long healing time. In these circumstances, the use of products that can accelerate enhance wound process is urgently needed. One breakthrough in therapy platelet-rich plasma (PRP). Platelet-rich autologous with a platelet concentration above normal value. This study literature review aiming to describe role PRP burn ...

Vol. 29, No. 5, 2017 635 Received May 17, 2016, Revised August 19, 2016, Accepted for publication September 1, 2016 Corresponding author: Byung Cheol Park, Department of Dermatology, Dankook University Hospital, 201 Manghyang-ro, Dongnam-gu, Cheonan 31116, Korea. Tel: 82-41-550-6485, Fax: 82-41-552-7541, E-mail: shinam73@ hotmail.com This is an Open Access article distributed under the terms of...

tergent. The detergent may enable the toxin to penetrate deeper into the cornea. We believe that these are the first reported cases of Surgilube use on the ocular surface. Because of the common use of Surgilube in the hospital setting and the similar appearance to certain ocular medications, it is unlikely that this is the first actual time its mistaken use has occurred. It is important to corr...

Reepithelialization during cutaneous wound healing involves numerous signals that result in basal keratinocyte activation, spreading, and migration, all linked to a loosening of cell-cell adhesion structures. The transcription factor Slug is required for this process, and EGF treatment of human keratinocytes induced activating phosphorylation of Erk5 that coincides with slug transcription. Acco...

Matrix metalloproteinase-10 (MMP-10) is expressed by macrophages and epithelium in response to injury, but its functions in wound repair are unknown. We observed increased collagen deposition and skin stiffness in Mmp10(-/-) wounds, with no difference in collagen expression or reepithelialization. Increased collagen deposition in Mmp10(-/-) wounds was accompanied by less collagenolytic activity...