Epidemiologic studies suggest that neurocysticercosis (NC) is the main cause of symptomatic epilepsy in developing countries. The association between NC and mesial temporal lobe epilepsy (MTLE) has been reported by several authors. Recent data have shown that the presence of NC does not influence the clinical and pathological profile in MTLE patients and suggest that not all cysticercotic lesio...

PURPOSE Epilepsy surgery is performed based on the assumption that medical refractory epilepsy will continue. Rarely seizure freedom occurs before surgery is performed, while the patient is being evaluated as an epilepsy surgery candidate. The aim of this study was to describe the number of children withdrawn from an epilepsy surgery programme due to unexpected seizure improvement. METHODS We...

BACKGROUND AND PURPOSE Resting-state networks including the DMN have been shown to be abnormal in adults with temporal lobe epilepsy. However, little is known about the DMN in children with medically refractory epilepsy. The aim was to determine whether there was a difference in the DMN in children with medically refractory epilepsy relative to controls. MATERIALS AND METHODS Eleven children ...

Abstract Background RHOBTB2 gene is associated with developmental and epileptic encephalopathy-64(DEE-64), which characterized by epilepsy, delay, microcephaly, unspecific facial dysmorphism, paroxysmal movement disorders. Most previous studies showed that the phenotypes of include encephalopathy(DEE) DEE Only one study patient variant had disorders no epilepsy. Case presentations Two cases var...

Awake craniotomy represents an essential option for surgical procedures requiring a patient’s participation in defining the extent of resection. This includes excision of epileptogenic foci, performed in patients with medically refractory epilepsy. Approximately 2 million Americans with a diagnosis of epilepsy are treated with Antiepileptic Drugs (AEDs), of these 20 percent continue to have sei...

Since the development of Deep Brain Stimulation (DBS) for Parkinson's Disease, DBS has been suggested as a treatment option for various other neurological disorders. Stimulation of deep brain structures for refractory epilepsy appears to be a safe treatment option with promising results. As research on the evaluation and optimization of DBS for refractory epilepsy may be difficult and unethical...

Case presentation: Boy, 4 years old. Born term, cesarean for oligohydramnios, without consanguinity. Mother with hypothyroidism, maternal uncle autism, cousin epilepsy and paternal cerebral palsy. Adequate neuropsychomotor up to 2 of age. At this age, started ataxic gait, refractory epilepsy, spasticity, language loss dysphagia. Multiple hospitalizations due bronchoaspiration pneumonia. Gastros...

Focal epilepsy accounts for approximately one-half to two-thirds of new-onset epilepsy in children. Etiologies are diverse, and range from benign epilepsy syndromes with normal neuroimaging and almost certain remission to focal malformations of cortical development or hippocampal sclerosis with intractable seizures persisting lifelong. Other important etiologies in children include pre-, peri-,...

Epilepsy affects between 0.5% and 1% of the population and starts in childhood in two-thirds of patients. Approximately 30% of patients with epilepsy who are less than 18 years of age have medically refractory seizures [1, 2]. Seizures may adversely impact intellectual functioning [3-6] and therefore good seizure control is of critical importance. Compared with the mature brain, the impact of s...

Background & Objective: Psychiatric disorders constitute a large part of illness burden in patients with refractory epilepsy. A careful presurgical psychiatric assessment is now an integral part of evaluation in most centers performing surgeries for refractory epilepsy. This study was undertaken to determine the prevalence of psychiatric disorders and outcome of the psychopathology in patients ...