Case Report We confirmed the Muckle-Wells syndrome phenotype of CAPS by NLRP3 genetic testing in a three generation family of Turkish Jewish origin, previously diagnosed with familial Behcet disease due to the presence of mucosal ulcers in several family members with the finding of the HLA-B51 antigen in at least one family member. Eight family members including a deceased grandfather, 4 of his...

Small bowel involvement is very common in Crohn’s disease. Ileocolonoscopy, cross-sectional imaging modalities, and video capsule endoscopy are the tools currently used to investigate such involvement. Herein we report case of a 47-year-old man with history ileocolic disease persistent, unexplained iron deficiency anemia. Capsule endoscopy, by accurately identifying small intestinal mucosal les...

objective(s): prostaglandins have been shown to mediate the gastro-protective effect of sodium hydrosulfide (nahs) but effect of nahs on mrna expression of prostaglandin e2 receptors (ep1, 3-4; eps) has not been investigated. therefore, this study designed to evaluate the effect of nahs on mrna expression of eps receptors in response to mucosal acidification and distention-induced gastric acid ...

the energy boom of the last decade has led to rapidly increasing wealth in the middle east, particularly in the oil and gas-rich gulf cooperation council (gcc) countries. this exceptional growth in prosperity has brought with it rapid changes in lifestyles that have resulted in a significant rise in chronic disease. in particular the number of people diagnosed with diabetes has increased dramat...

Dendritic cells (DCs) modulate B-cell differentiation, activation, and survival mainly through production of growth factors such as B lymphocyte stimulator (BLyS/BAFF). DC populations have been reported to be affected in number, phenotype and function during HIV infection and such alterations may contribute to the dysregulation of the B-cell compartment. Herein, we reflect on the potential impa...