background indomethacin is a nsaid (non-steroidal anti-inflammatory drug) that is used in treatment of pain and inflammatory. immediate and sustained release products of this drug have side effects, so a proper replacement is needed. use of the medicine via topical and cutaneous routs has advantages such as avoiding side effects on gastrointestinal; and supplying an amount of medicine in plasma...

chemotherapy research highly prioritizes overcoming the multidrug resistance (mdr) in human tumors. liposomal formulation of fluoxetine, as a fourth generation chemosensitizer, was constructed and characterized for percent entrapment, release profile, morphology, particle size, zeta potential and stability. liposomes were prepared using different active loading techniques. the influence of diff...

A common recommendation for implementing time-out procedures is to include a release contingency such that the individual is not allowed to leave time-out until no problem behavior has occurred for a specific amount of time (e.g, 30 s). We compared a fixed-duration time-out procedure to a release contingency time-out procedure with 4 young children (3- and 4-year-olds) using a reversal and mult...

In this study, the effects of various hydrophilic (HPMC and Carbopol 971) and plastic (Ethylcellulose and Eudragit RL100) polymers on the release profile of diltiazem HCl from matrix tablets were evaluated in-vitro. For this purpose, tablets containing 60 mg of diltiazem HCl along with various amounts of the aforementioned polymers were prepared using the wet granulation technique. Tablets prep...

Microencapsulation of liquid orange oil as a common flavoring agent in food industries by complex coacervation in a gelatin – gum arabic polymeric wall system was studied. At a fixed ratio of 10% w/v as concentration of the materials used in this study, trend of changes of microencapsulation process variables using different wall polymeric contents along with varying levels of the core to wall ...

Arrayed Ti6Al4V nanotubes (TNT) coated with hydroxyapatite (HA) were synthesized via electrochemical anodization method. Paracetamol was loaded onto TNT-HA electrode. Effects of anodization, nanotube formation and hydroxyapatite deposition on sorption and release of the drug were investigated. Saturation time of paracetamol on the anodized samples was 30% shorter than the hydroxyapatite-coated ...

in this study, attempts were made to evaluate the effect of various acrylic acid based carbopols on the release profile of a beta-adrenoreceptor blocking drug, propranolol hcl, from matrix-type tablets invitro. for this purpose, tablets containing 160 mg of propranolol hcl along with various amounts of carbopols 934 (c934), 971 (c971), 974 (c974) and pemulen (pem) were prepared using the wet gr...

In this study, the effects of various hydrophilic (HPMC and Carbopol 971) and plastic (Ethylcellulose and Eudragit RL100) polymers on the release profile of diltiazem HCl from matrix tablets were evaluated in-vitro. For this purpose, tablets containing 60 mg of diltiazem HCl along with various amounts of the aforementioned polymers were prepared using the wet granulation technique. Tablets prep...

background: many attempts have been performed and continued for improvement of dental amalgam properties during last decades. the aim of present research was fabrication and characterization of amalgam/titania nano composite and evaluation of its corrosion behavior. materials and methods: in this experimental research, nano particles of titania were added to initial amalgam alloy powder and the...