Fourteen women with cyclical oedema and six healthy female controls were investigated by use of a test in which thyrotrophin releasing hormone and luteinising hormone releasing hormone were given. Significant differences in the responses of prolactin, luteinising hormone, and follicle stimulating hormone were observed in the patients. These findings suggest that there may be a hitherto unrecogn...

Information theoretic approaches can be used to quantify information transfer via cell signaling networks. In this study, we do so for gonadotropin-releasing hormone (GnRH) activation of extracellular signal-regulated kinase (ERK) and nuclear factor of activated T cells (NFAT) in large numbers of individual fixed LβT2 and HeLa cells. Information transfer, measured by mutual information between ...

Effective contraception is necessary in countries where limiting population growth has become a public policy imperative. The main antigenic targets for contraceptive vaccine development can be listed as following: 1) sperm antigens, 2) zona pellucida antigens, 3) gonadotrophin-releasing hormone, 4) chorionic gonadotrophin, 5) other protein/peptide hormones (follicle-stimulating hormone, lutein...

Ovulation was successfully induced with luteinising hormone releasing hormone in 28 women with hypothalamic amenorrhoea who had failed to respond to treatment with clomiphene. Luteinising hormone releasing hormone was administered in a pulsatile manner with miniaturised automatic infusion systems. The rate of ovarian follicular maturation, as monitored by serial pelvic ultrasonography, was simi...

BACKGROUND Isolated adrenocorticotropic hormone (ACTH) deficiency is a pituitary disorder characterized by reduction only in the secretion of ACTH. Although the underlying mechanism remains to be elucidated, numbers of cases with this entity have been increasing. We experienced a case presenting with gait disturbance necessitating differential diagnosis from idiopathic normal pressure hydroceph...

OBJECTIVE: The aim of this study is to evaluate the outcomes gonadotropin-releasing hormone agonist treatment for ovarian cysts, which are developed during tamoxifen use due breast cancer. STUDY DESIGN: This was a retrospective cohort including patients who were under stage I-III cancer and administered leuprolide acetate cysts with low malignancy risk between 2012-2020. RESULTS: Leuprolide tot...