AIMS It is common to advise that analgesics, and especially non-steroidal anti-inflammatory drugs (NSAIDs), be taken with food to reduce unwanted gastrointestinal adverse effects. The efficacy of single dose analgesics depends on producing high, early, plasma concentrations; food may interfere with this. This review sought evidence from single dose pharmacokinetic studies on the extent and timi...

In this paper, a newsboy model is developed under uniformly distributed lead-time and demand that is an appropriate assumption in obtaining optimal relief inventory of humanitarian disasters. It is noteworthy that limited historical data are in hand on relief operations. Hence, analytical and approximate solutions for optimal relief order quan­tity were derived. The effect of lead-time uncertai...

microstructural evolutions of twinning induced plasticity (twip) steel during tensile straining wereinvestigated by in situ sem observations. the results indicated that slip lines and mechanical twins aswell as surface relief were increased with increasing strain, resulting in a stepped surface. additionally,these deformation mechanisms could change the shape of each grain via shear and rotatio...

The coordination problem of relief items’ distribution operations is essential in humanitarian relief chains. If the coordination is proper, it will improve the response phase to the crisis. In order to improve the coordination in humanitarian relief chains, distribution and warehousing operations of relief items were outsourced to the third-party logistics. In this paper, the procurement-distr...

BACKGROUND n-Hexane is a well-known neurotoxicant. Polyneuropathy due to occupational n-hexane exposure has been reported worldwide, however, our case is the first report in the Chinese herb industry. CASE PRESENTATION A 25-year-old Asian man experienced progressive weakness and numbness in his hands and feet after working as an operator in a Chinese medicine pharmaceutical plant for the manu...

b a c k g r o u n d & aim: following the bam earthquake, relief teams and individual volunteers’influx in the scene. we conducted this survey to determine the needs and health status of relief workers when they were in the scene. methods  & materials:   this  was a concurrent  nested  mixed-method  survey  that  the qualitative nested   in  a  quantitative   approach.   interviews   were   thro...

Background and Aims Since alcohol use disorders are among the most prevalent and destructive mental disorders, it is critical to address factors contributing to their development and maintenance. Drinking motives are relevant driving factors for consumption. Identifying groups of drinkers with similar motivations may help to specialize intervention components and make treatment more effective a...