Renal function was evaluated in 40 patients with fulminant hepatic failure, They were divided into two groups on the basis of glomerular filtration rates greater than 40 ml/min or less than 25 ml/min. A number of patients in group 1 had markedly abnormal renal retention of sodium together with a reduced free water clearance and low potassium excretion which could be explained by increased proxi...

how to cite this article: afsharkhas l, tavasoli a. renal function in children with febrile convulsions.iran j child neurol. 2014 autumn;8(4):57-61. abstract objective febrile convulsions (fc) are the most frequent seizure disorder in children. some studies have detected serum electrolyte disturbances in patients with fc. this study determines serum electrolytes, renal function tests, and frequ...

Renal and hormonal abnormalities, usually manifested as oedema or hyponatraemia, are encountered frequently in patients with chronic obstructive pulmonary disease (COPD). The exact incidence of clinically significant oedema and hyponatraemia has not been documented. In advanced disease some degree of oedema is observed in a large proportion of patients; the pattern of hyponatraemia parallels th...

Preeclampsia (pregnancy-induced hypertension) is a disorder specific to pregnancy and the pathological changes it causes regress after delivery. Reversible hyperuricaemia is the most characteristic biochemical feature of preeclampsia, first noted nearly 60 years ago by Slemons and Bogert (1917). More recently, Chesley and Williams have shown that the high plasma urate is the result of renal tub...

Obesity, a global health problem, has an ever increasing prevalence.1 Because excess weight is a major risk factor for high blood pressure, this results in a continuous rise in the prevalence of hypertension.2 In this issue of Hypertension, Chughtai et al3 identified a potential pathogenic link between renal sinus adiposity and hypertension in humans. Adipose tissue can be divided into compartm...

Today, an increase in vancomycin dose has been proposed to ensure efficacy. However, the risk of nephrotoxicity will increase with the dose. This study was aimed at evaluating the dosage regimens of vancomycin in pediatric patients based on pharmacokinetics/pharmacodynamics (PK/PD) and to optimize dosage individualization. Population pharmacokinetics analysis was performed on 155 Chinese childr...

background and objective: cystinosis is a rare inherited disease that leads to renal failure. fanconi syndrome is the major renal involvement in cystinosis patients. renal transplantation is the treatment of choice in cystinosis children with end-stage renal disease (esrd).  the study aimed to assess the outcome of renal transplantation in iranian children with cystinosis. methods: this retrosp...

Diuretics are frequently required to treat fluid retention in patients with congestive heart failure (CHF). Unfortunately, they can lead to a decline in renal function, electrolyte depletion, and neurohumoral activation. Arginine vasopressin (AVP) promotes renal water reabsorption via the V2 receptor, and its levels are increased in CHF. This study was designed to assess the effects of a single...

Today, an increase in vancomycin dose has been proposed to ensure efficacy. However, the risk of nephrotoxicity will increase with the dose. This study was aimed at evaluating the dosage regimens of vancomycin in pediatric patients based on pharmacokinetics/pharmacodynamics (PK/PD) and to optimize dosage individualization. Population pharmacokinetics analysis was performed on 155 Chinese childr...