BACKGROUND Cardiovascular risk is increased in the early stages of chronic kidney disease (CKD) and also found to be ongoing in renal transplant (Rtx) patients. As a sign of atherosclerosis, increased carotid intima-media thickness (CIMT) has been widely accepted as a strong predictor of cardiovascular disease (CVD) and mortality in CKD patients. A novel markers, soluble tumor necrosis factor-l...

A number of case reports and case series of patients with Wegener’s granulomatosis, microscopic polyangiitis and Churg-Strauss syndrome have supported the use of rituximab (RTX) for the treatment of refractory ANCA-associated vasculitis (AAV). Whether B cell depletion with RTX could replace cyclophosphamide as a first-line therapy for patients with severe AAV remains to be proven. Two studies, ...

ureteral obstruction is relatively common after renal transplantation. a rare cause is the inguinal herniation of the transplant ureter. we report a case of late allograft renal transplant failure due to ureteral herniation as well as ureterovesical junction stenosis.

Background and Objective: Cystinosis is a rare inherited disease that leads to renal failure. Fanconi syndrome is the major renal involvement in cystinosis patients. Renal transplantation is the treatment of choice in cystinosis children with end-stage renal disease (ESRD).  The study aimed to assess the outcome of renal transplantation in Iranian children with cystinosis. Methods: This...

BACKGROUND Renal involvement in rheumatoid arthritis (RA) is common and has a negative impact on patient survival. Only few cases have been reported of necrotizing glomerulonephritis (GN) associated with myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) in patients with RA. CASE PRESENTATION We report a patient with RA who developed a necrotizing GN associated with ANCA-MPO, tre...

BACKGROUND Measurements of aortic stiffness [aortic pulse wave velocity (PWV) and augmentation index (Alx)] have been established as powerful predictors of survival on hemodialysis (HD). Abnormal endothelial-dependent and endothelial-independent vascular reactivity and increased arterial stiffness are commonly described in HD patients. There is, however, a lack of information on the comparative...

To the Editor: Varied dosing regimens of rituximab (RTX) have been successfully used in the management of primary membranous nephropathy (PMN). An ideal RTX dose and the long-term adverse effect of a larger cumulative dose are not clear. CD19 levels are used to gauge the drug effect. Economic viability is a major part of any new therapeutic regimen. Low-dose RTX (100 mg) has been successfully u...

background: today, renal disease is one of the major worldwide health problems. it has a high prevalence, which increases 8% annually. incidence of renal disease and treatment techniques can affect the quality of life, health status and social roles of patients. the aim of the current study was to determine the quality of life of dialysis and kidney transplant patients and compare it to healthy...

patients and methods five hundred and sixteen serum samples of the patients undergoing hemodialysis and kidney transplantation from various cities of khuzestan province were collected. anti-hepatitis g e2 antibodies were investigated by elisa method. rnas were extracted from serums and hepatitis g rna was detected by rt-pcr. results of the 516 samples, 38 (7.36%) specimens were positive for ant...