The ability to predict which alien plants will transition from naturalized to invasive prior to their introduction to novel regions is a key goal for conservation and has the potential to increase the efficacy of weed risk assessment (WRA). However, multiple factors contribute to plant invasion success (e.g., functional traits, range characteristics, residence time, phylogeny), and they all mus...

The pharmacokinetic characteristics of cefepime were determined after first dose (n = 35) and again under steady-state conditions (n = 31) with a group of 37 infants and children. In eight subjects, a cefepime dose given by intramuscular injection was substituted for an intravenous dose, and disposition characteristics were studied again. Study subjects ranged in age from 2.1 months to 16.4 yea...

This paper develops and defends a coherentist account of reasons. I develop three core ideas for this defense: a distinction between basic reasons and noninferential justification, the plausibility of the neglected argument against first philosophy, and an emergent account of reasons. These three ideas form the backbone for a credible coherentist view of reasons. I work toward this account by f...

Abstract Ecological residence is the direction of residence development in 21 century; it is the final choice of people when their living standard becomes high enough. Ecological Residence pursues high harmony and unification among nature, buildings and human, and improves the ecological environment and living quality of human. This article analyzes the problems in developing ecological residen...

Recent decision-making research claims to establish that, in violation of Savage’s normative sure-thing principle, individuals often wait to acquire noninstrumental information and subsequently base their decisions upon this information. The current research suggests that characterizing individuals as pursuing noninstrumental or useless information may be overstated. Through a series of experim...

BACKGROUND Adult leg length is influenced by nutritional intake in childhood. Shorter leg length has been found to be associated with adverse health outcomes in late life, including dementia. Smaller head circumference has also been found to be associated with dementia. The independence of these two potential markers of risk for dementia has not been investigated. METHODS Community residents ...

Drug discovery is expensive and high-risk. Its main reasons of failure are lack of efficacy and toxicity of a drug candidate. Binding affinity for the biological target has been usually considered one of the most relevant figures of merit to judge a drug candidate along with bioavailability, selectivity and metabolic properties, which could depend on off-target interactions. Nevertheless, affin...

The residence time measures the time spent by a water parcel or a pollutant in a given water body and is therefore widely used in environmental studies. The adjoint method introduced by Delhez et al. (2004) to compute this diagnostic is revised here to take into account the effect of the initialization and of the boundary conditions. In addition to the equation for the mean residence time, it i...

Variability of residence time in the Tropical Tropopause Layer during Northern Hemisphere winter K. Krüger, S. Tegtmeier, and M. Rex Leibniz-Institute for Marine Sciences at Kiel University (IFM-GEOMAR), Kiel, Germany Environment Canada, Toronto, Canada Alfred Wegener Institute for Polar and Marine Research, Potsdam, Germany Received: 18 April 2009 – Accepted: 15 May 2009 – Published: 28 May 20...