Standard treatment for colorectal cancer includes surgery, radiotherapy, and chemotherapy. Conventional chemotherapeutic agents used in such as 5-fluorouracil, capecitabine which is oral form of irinotecan, oxaliplatin. One the major challenges chemotherapy considered drug resistance. Drug resistance occurs many different mechanisms alteration tumor microenvironment, growth kinetics, genetic va...

skeletal muscle may develop adaptive chaperone and enhancementdefense system through daily exercisestimulation. the present study investigated resistance and exhaustion training alters the expression of chaperoneproteins. these proteins function to maintain homeostasis, facilitate repair from injury and provide protection. exercise-induced production of hsps in skeletal muscle and peripheral le...

The enzymatic defense mechanisms of Gorgonia ventalina to the fungal pathogen Aspergillus sydowii may play important roles in colony resistance to infection. In this study, we examined the role of the superfamily of peroxidase enzymes in the coral response to a naturally occurring pathogen. We examined the inducibility of peroxidases by experimentally exposing corals to A. sydowii and found tha...

Pseudomonas tabaci (Wolf and Foster) Stevens, produces an exotoxin, detectable as a bacteriumfree, chlorotic halo, surrounding the necrotic focus of infection in the leaf of a susceptible host at the site of inoculation (Braun, 1955). Garber and Heggestad (1958) reported that species of Nicotiana and varieties of Nicotiana tabacum differed in their susceptibility, ranging from highly susceptibl...

Colistin relates to the polymyxin group of antibiotics. This antibiotic is still used to destroy gram-negative bacteria as a last resort. However, resistance to this antibiotic has been reported and is appearing day by day. Not much information is available on the exact mechanisms of resistance to this antibiotic. Also, not enough information about pharmacokinetics and pharmacodynamics is avail...