The peripheral vascular response to severe exercise was studied in 11 healthy conscious dogs instrumented with Doppler ultrasonic flow probes on the mesenteric, renal, and iliac arteries, and miniature pressure gauges in the aorta. The response to severe exercise was restudied in six of these dogs after recovery from a second operation producing complete heart block by the injection of formalin...

Because ethanol abusers are susceptible to pancreatitis in animal models, and interruption of the pancreatic circulatory supply may also cause pancreatitis, we studied the effect of ethanol infusion on pancreatic blood flow. We administered ethanol 0.5 g/kg and 1.5 g/kg iv, to 35 conscious dogs (ethanol blood levels, 117 ± 10 (SD) and 297 ± 67 mg/100 ml, respectively). Measurements were made of...

Diabetes mellitus is the most common metabolic diseases. It is estimated that its worldwide prevalence will reach to 21% up to 2050. In Iran the prevalence of diabetes is estimated to be about 14%. It divided in two categories: type 1 and type 2. Diabetes type 1 is due to absolute deficiency of insulin secretion, and type 2 characterised by resistances to insulin and its inadequate compensation...

Reductions in basal leg blood flow have been implicated in the pathogenesis of metabolic syndrome and functional impairment in humans. We tested the hypothesis that reductions in basal whole leg blood flow with age are either absent or attenuated in those who perform regular strength training. A total of 104 normotensive men aged 20-34 yr (young) and 35-65 yr (middle aged), who were either sede...

1. The effect of infusion of isotonic saline on the circulation in the renal cortex in the dog was investigated by an external counting technique involving measurement of the transit times for 'Krypton and l 311-labelled albumin after rapid injection into the renal artery. 2. During saline infusion superficial renal cortical blood flow and overall cortical blood flow rose by 23 and 15%, respect...