Textbooks on response surface methodology emphasize the importance of lack-of-fit tests when fitting response surface models, and stress that, to be able to test for lack of fit, designed experiments should have replication and allow for pure-error estimation. In this paper, we show how to obtain pure-error estimates and how to carry out a lack-of-fit test when the experiment is not completely ...

xanthan gum is an extracellular polysaccharide produced by various xanthomonas species such as x. campestris . the objective of present study was to investigate the influence of different carbon and nitrogen sources on xanthan gum production by x. campestris . using an experimental response surface methodology (rsm) complemented with a central composite design (ccd), the impact of peptone, lact...

osmotic dehydration under discontinuous reduced pressure is one of the new methods of preparation fruits and vegetable processing with in view of good health. processing of foods at high temperatures used to cook them can cause the formation of carcinogenic substances like acrylamide, and this risk remains even if the trans-fat is removed. the low temperatures employed in this method resulted i...

the aim of this study was to optimize the encapsulation conditions of garlic oil (go) with β-cyclodextrin (go/β-cd) inclusion complex by the co-precipitation method. response surface optimization of encapsulation of go with β–cd was performed with a three-variable, three-level and the optimum conditions were as follows: temperature: 35oc, core/wall: 8/100, and wall/solvent: 5.5/100. the complex...

probiotics are defined as living microorganisms with beneficial effects on the host. probiotics, according to the least negative effect on the body, are considered as a good alternative to chemical drugs. lactobacillus acidophilus is used as a probiotic that is able to reduce cholesterol level in the blood. the effect of various concentrations of carbon, nitrogen and phosphorus for enhancing th...

In the tube drawing process, there are a bunch of parameters which play key role in process performance. Thus, finding the optimized parameters is a controversial issue. Current study aimed to produce a squared section of round tube by tube sinking process. To simulate the process finite element method (FEM) was used. Then, to find a meaningful kinship between process input and output parameter...

Many industrial experiments involve some factors whose levels are harder to set than others. The best way to deal with these is to plan the experiment carefully as a split-plot, or more generally a multi-stratum, design. Several different approaches for constructing splitplot type response surface designs have been proposed in the literature since 2001, which has allowed experimenters to make b...

to enhance the understanding of the impact of obstacle buildings on pollution transportationand dispersion in the atmospheric boundary layer, it is necessary to know the atmospheric flow characteristics over terrains. wind flow characteristics in a boundary layer over a step-shaped cliff topography model with rough and smooth surfaces were studied numerically using computational fluid dynamics ...