Sleep disturbances are important nonmotor symptoms in Parkinson's disease (PD) that are associated with a negative impact on quality of life. Restless legs syndrome (RLS), which is characterized by an urge to move the legs accompanied by abnormal leg sensations, can coexist with PD, although the pathophysiology of these disorders appears to be different. RLS and PD both respond favorably to dop...

Objective: Diabetes is a global epidemic with India estimated to have the highest prevalence of 79.4 million by 2030. RLS is a common yet undiagnosed comorbidity causing significant distress. We aimed to analyze association between restless legs syndrome (RLS) and type 2 diabetes. Method: One hundred fifty six Type 2 Diabetes mellitus (T2DM) and eighty eight non-diabetic control, were assessed ...

1 Neurophysiopathology Unit, Department of Systems Medicine, Sleep and Epilepsy Medicine Centre, Tor Vergata University and Hospital, Rome, Italy 2 IRCCS Neuromed, Pozzilli, Italy 3 Neurology, Department of Systems Medicine, Tor Vergata University and Hospital, Rome, Italy 4 Clinica Neurologica Ospedale S. Eugenio, Rome, Italy 5 IRCCS Santa Lucia Foundation, Rome, Italy *Correspondence: a_romig...

1 Motivation Both legged and limbless animals often exhibit various types of locomotion by adapting to the current circumstances encountered in real time. This ability has been honed by evolutionary selection pressure, and there likely exists an ingenious mechanism that underlies any type of locomotion. Clarifying this mechanism will lead us to elucidate the fundamental principle of animal loco...

BACKGROUND/AIM Sleep disorders are more common in people with rheumatoid arthritis (RA). We aimed to determine the sleep quality in adult and elderly people with RA and the factors associated with sleep disorders in each group. MATERIALS AND METHODS The study was conducted with 182 patients (83 elderly and 99 adult patients) diagnosed with RA. Data were collected through a patient identificat...

Sir, The association of restless legs syndrome with polyneuropathy, especially with involvement of small sensory fibres, is suggested by several observations (Iannaccone et al., 1995; Polydefkis et al., 2000; Gemignani et al., 2006); however, it is still controversial (Hattan et al., 2009). Bachmann et al. (2010) investigated 34 consecutive outpatients with restless legs syndrome from their Mov...

INTRODUCTION We describe a potential new treatment option for patients suffering from restless legs syndrome. Contemporary treatment for restless legs syndrome consists mostly of dopaminergic drugs that leave some patients feeling nauseated and dizzy. A non-invasive, drug-free option would open new doors for patients suffering from restless legs syndrome. CASE PRESENTATION A 69-year-old Cauca...

OBJECTIVE To investigate clinical features, iron metabolism and neuroinflammation in Parkinson's disease (PD) patients with sleep disorders (SD). METHODS 211 PD patients were evaluated by Pittsburgh Sleep Quality Index (PSQI) and a body of scales for motor symptoms and non-motor symptoms. 94 blood and 38 cerebral spinal fluid (CSF) samples were collected and iron and its metabolism-relating p...

STUDY OBJECTIVES To determine the prevalence of sleep complaints in adults in Colombia at different altitudes. DESIGN Cross-sectional, population-based and observational study. SETTING Urban areas in three cities (Bogotá, Bucaramanga, Santa Marta) located between 15 and 2640 masl. Subjects Over 18 years old. INTERVENTIONS Epworth sleepiness scale (ESS), Pittsburgh sleep quality index (PSQ...