BACKGROUND Data on reverse remodeling of the left atrium (LA) and left ventricle (LV) after restrictive annuloplasty in patients with dilated cardiomyopathy are scarce, and follow-up studies are performed with echocardiography. METHODS AND RESULTS Twenty patients with dilated cardiomyopathy and severe mitral regurgitation selected for restrictive mitral annuloplasty underwent serial MRI studi...

Cardiac amyloidosis (CA) is characterized by progressive pathological deposition of amyloid fibrils in the myocardial interstitium, resulting ultimately restrictive cardiomyopathy. The accumulating heart are most commonly misfolded immunoglobulin light chains (in case AL amyloidosis) or transthyretin (ATTR), latter being either wild-type variant conformation.

Endomyocardial disease is a restrictive cardiomyopathy that includes Löffler endocarditis, which is characterized by hypereosinophilia, and endomyocardial fibrosis, which is not. Echocardiography enables cardiac function and anatomy to be assessed and the differential diagnosis of other causes of restrictive disease, but magnetic resonance imaging provides information about the tissue itself. F...

Amyloid cardiomyopathy is a rare disease characterized by the extracellular deposition of insoluble fibrils resistant to proteases. It may be secondary to chronic inflammatory conditions, hereditary diseases or to the production of a light chain of monoclonal immunoglobulin. This often leads to an infiltrative cardiomyopathy with a restrictive pathophysiology, conventionally associated with sig...

Desminopathies are a largely autosomal dominant group of rare diseases caused by mutations in the desmin gene. Because desmin is the main component of intermediate filaments in cardiac, skeletal, and smooth muscle and of Purkinje fibers, these conditions are characterized by skeletal myopathy and cardiomyopathy (mainly restrictive) with arrhythmias or conduction disorders. The aim of our presen...

7. Chew CYC, Ziady GM, Raphael MJ, Nellen M, Oakley CM: Primary restrictive cardiomyopathy. Non-typical endomyocardial fibrosis and hypereosinophilic heart disease. Br Heart J 39: 399, 1977 8. Morales DD, Wagner RL, Abelmann WH: Right and left ventricular compliance in acute and subacute trypanosomal myocarditis. Cardiovasc Res 7: 201, 1973 9. Kaltenbach M, Hopf R, Kober G, Bussman WD, Keller M...

A 58 years old male with a long-standing history of HLA-B27 positive ankylosing spondylitis presented with increasing fatigue and dyspnea on exertion. He had left ventricular dysfunction and enlargement, flail right coronary leaflet of aortic valve with severe eccentric aortic insufficiency along with left ventricular non-compaction in echocardiography. The most common cardiac manifestations of...

Left atrial ball valve thrombus is an unusual condition, especially in patients with normal mitral valve. In the present case, we describe a 61-year-old female with restrictive cardiomyopathy who presented with a large left atrial ball valve thrombus, which subsequently embolized to right carotid artery and was treated with intravenous thrombolysis. This case provides useful insight into the ge...

BACKGROUND Diabetes is often associated with an abnormal diastolic function. However, there are no data regarding the contribution of diastolic dysfunction to the development of heart failure (HF) in diabetic patients after acute myocardial infarction. METHODS AND RESULTS A total of 1513 patients with acute myocardial infarction (417 diabetic) underwent echocardiographic examination during th...