BACKGROUND Non-compliance with childhood acute lymphoblastic leukemia (ALL) protocol is an important determinant of poor treatment outcome. Non-compliance with protocol may not only concern parents or patients, but may also concern health-care providers (HCP). Our study examines the accuracy of leukemia risk classification and attitude of HCP toward protocol compliance in Indonesia. PROCEDURE...

Objective: The selection of beam orientations, which is a key step in radiation treatment planning, is particularly challenging for non-coplanar radiotherapy systems due to the large number of candidate beams. In this paper, we report progress on the group sparsity approach to beam orientation optimization, wherein beam angles are selected by solving a large scale fluence map optimization probl...

Secretion systems require high-fidelity mechanisms to discriminate substrates among the vast cytoplasmic pool of proteins. Factors mediating substrate recognition by the type VI secretion system (T6SS) of Gram-negative bacteria, a widespread pathway that translocates effector proteins into target bacterial cells, have not been defined. We report that haemolysin coregulated protein (Hcp), a ring...

INTRODUCTION Not all smokers receive tobacco cessation advice from health care providers (HCPs) and, although factors associated with receiving HCP advice to quit smoking and the effectiveness of such advice have been examined, no recent study has explored differences between types of HCPs (eg, physicians vs dentists). Our objective was to determine the prevalence of HCP-delivered advice and th...

The potential for a particle to crush under one-dimensional compression is critically dependent on the coordination number of that particle. Neighboring particles decrease deviatoric forces at contacts, which reduces tensile stress and subsequent fracture propagation in the crushable particle. This phenomenon is called “shielding effect”. In this paper, we model a sand particle as a spherical c...

BACKGROUND AND AIMS Despite effective vaccine available, hepatitis A remains a significant cause of morbidity and mortality worldwide including acute liver failure, transplantation and death. Vaccination rates for hepatitis A in the general population are low. Rates of hepatitis A vaccination in healthcare personnel (HCP) are unknown. We studied vaccination rate to hepatitis A in a cohort of HC...

Hexagonal close-packed iron (hcp-Fe) is a main component of Earth's inner core. The difference in density between hcp-Fe and the inner core in the Preliminary Reference Earth Model (PREM) shows a density deficit, which implies an existence of light elements in the core. Sound velocities then provide an important constraint on the amount and kind of light elements in the core. Although seismolog...

The aim of this study was to measure which three-dimensional spatiotemporal and kinematic parameters differentiate upper limb movement characteristics in children with hemiplegic cerebral palsy (HCP) from those in typically developing children (TDC), during various clinically relevant tasks. We used a standardized protocol containing three reach tasks (forwards, upwards, and sideways), two reac...

This study examines the effect of silica fume (SF) as a partial replacement for cement to prevent strength retrogression in hardened paste (HCP) and mortar at elevated temperatures. An experimental procedure was conducted on 320 specimens, replacing 0, 10, 20, 30% by weight with SF. The residual compressive specimens evaluated room temperature (25 °C) 100, 200, 300, 400 °C 7, 28, 56 days. resul...

Agrobacterium tumefaciens is a plant-pathogenic bacterium capable of secreting several virulence factors into extracellular space or the host cell. In this study, we used shotgun proteomics analysis to investigate the secretome of A. tumefaciens, which resulted in identification of 12 proteins, including 1 known secretory protein (VirB1*) and 11 potential secretory proteins. Interestingly, one ...