purpose : evaluating the effects of memantine on visual function after scleral buckling for rhegmatogenous retinal detachment (rrd) methods : in a double blind prospective randomized clinical trial, 61 patients with clinical diagnosis of less than 4 weeks macula-off rrd who had successful scleral buckle surgery had been selected and divided into two randomized groups. thirty of them received 5 ...

purpose: to evaluate the anatomical and functional outcomes of using heavy silicone oil as an internal tamponade for complicated cases of retinal detachment associated with proliferative vitreoretinopathy involving inferior retinal quadrants methods: 55 eyes from 55 patients with complicated retinal detachments enrolled in this interventional case series study. all eyes underwent standard three...

BackgroundSince the poor prognosis of uveal melanoma with distant metastasis, we intended to screen out possible biomarkers for metastasis risk and establish a nomogram model predicting (UVM) metastasis.MethodsTwo datasets UVM (GSE84976, GSE22138) were selected. Data was analyzed by R language, CTD database GEPIA.ResultsThe co-upregulated genes two datasets, HTR2B, CHAC1, AHNAK2, PTP4A3 identif...

BACKGROUND Spontaneous bullous serous retinal detachment (RD) with subretinal exudation complicating idiopathic central serous chorioretinopathy (ICSC) is a rare and infrequently described clinical entity. Clinical observations are described on this variant form in 11 patients, the largest series reported to date. METHODS 13 eyes of 11 Indian patients having this entity were followed up clini...

Dear Editor, Macular hole (MH) with retinal detachment (RD) predominantly occurs in highly myopic eyes, and is a major vision-threatening complication in pathologic myopia [1]. Treatment of MH with RD results in lower anatomic success rates and poorer functional outcomes than MH without RD. Spontaneous resolution of MH with RD is extremely rare; spontaneous resolution of MH without RD is report...

OBJECTIVE This study compared the clinical outcomes between 23-gauge (23-G) vitrectomy and 20-gauge (20-G) vitrectomy for the repair of retinal detachment (RD). METHODS A retrospective comparative analysis of 135 RD patients was conducted between January, 2013 and September, 2014 in the Ophthalmology Department of the Affiliated Hospital of Weifang Medical College. The clinical outcomes of RD...

PURPOSE To evaluate the feasibility, efficacy and safety of strict prone posturing taken for 2 hours after operation in preventing the occurrence of unintentional retinal displacement in elderly patients operated on for retinal detachment (RD). METHODS Twenty patients aged 60 or more with diagnosis of macula-off RD were asked to keep a strict face-down posturing for 2 hours after vitrectomy a...

to review the available data regarding the current management of non-complex rhegmatogenous retinal detachment and to propose a new decision-making algorithm aimed to improve the single surgery success rate for mid-severity rhegmatogenous retinal detachment, this study performed. an online review of pubmed database was performed, searching for all available manuscripts regarding anatomical and ...

BACKGROUND A 70-year-old woman with retinitis pigmentosa experienced an epiretinal membrane (ERM) formation and a tractional retinal detachment (RD) following subretinal administration of palucorcel (CNTO 2476), a novel human umbilical tissue-derived cell-based therapy, as part of a Phase I study. The clinical course and results of a histologic examination of the ERM, which was peeled during su...

PURPOSE Traditionally, preoperative posturing consisting of bed rest and positioning is prescribed to patients with macula-on retinal detachment (RD) to prevent RD progression and detachment of the fovea. Execution of such advice can be cumbersome and expensive. This study aimed to investigate if preoperative posturing affects the progression of RD. DESIGN Prospective cohort study. PARTICIP...