Retinal vascular lesions are the most common ophthalmologic manifestation of systemic lupus erythematosus (SLE), occurring in 3% to 29% of cases, generally late in the disease. More rare is the severe vaso-occlusive disease, often termed "retinal vasculitis", which includes central retinal artery occlusion, multifocal arteriolar occlusions, extensive capillary nonperfusion and central venous oc...

A 38-year-old man who died from systemic Behçet's disease had previously suffered from severe, recurrent bilateral retinal vasculitis, and anterior uveitis for 10 years. Immunopathological examination of the eyes postmortem revealed marked hyaline thickening of the retinal and optic nerve vessels. The vessels had an intramural and perivascular infiltrate of T lymphocytes which stained positivel...

BACKGROUND The purpose of this study is to report the clinical features and visual outcome of branch retinal artery occlusion (BRAO) associated with posterior uveitis. This is a retrospective study including the 18 eyes of 18 patients. All patients underwent a complete ophthalmic evaluation. Fundus photography, fluorescein angiography, and visual field testing were performed in all cases. RES...

Purpose An independent Safety Review Committee (SRC), supported by Novartis Pharma AG, analyzed investigator-reported cases of intraocular inflammation (IOI), endophthalmitis, and retinal arterial occlusion in the phase 3 HAWK HARRIER trials brolucizumab versus aflibercept neovascular age-related macular degeneration (nAMD). Design A post hoc analysis a subset data from two 2-year, double-maske...

BACKGROUND Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome presents with characteristic clinical manifestations such as aneurysms at arteriolar bifurcations and optic nerve and retinal vascular inflammation. Regression of such features on treatment with anti-tubercular therapy (ATT) combined with corticosteroids has not been reported in literature. FINDINGS A 30-...

BACKGROUND Coxsackieviruses are members of a group of viruses called the enteroviruses, which may cause respiratory and gastrointestinal symptoms, erythema, meningoencephalitis, myocarditis, pericarditis, and myositis. Unilateral acute idiopathic maculopathy caused by coxsackievirus A16 has been associated with hand, foot, and mouth disease, but only a few reports describe retinitis associated ...

Abstract Eales’ disease is a retinal vasculitis characterized by inflammation, ischemia, and neovascularization. Exact pathogenesis of this yet to be found out. We present 29-year-old male, diagnosed with in both eyes persistent intraocular inflammation. Enucleation the pthisical right eye was subjected for histopathological examination immunohistochemistry molecular biologic study mycobacteria...

INTRODUCTION Vitreous hemorrhage is one of the most common differential diagnoses of sudden painless decrease in vision. OBJECTIVE To find out the etiology of vitreous hemorrhage in cases of vitreous hemorrhage at a tertiary eye centre in Nepal. MATERIALS AND METHODS This was a hospital-based cross-sectional study done over a period of one-and-a-half years. One hundred and one subjects with...