OBJECTIVES To describe the use of systematic reviews or overviews (systematic reviews of systematic reviews) to synthesize quantitative evidence of intervention effects across multiple indications (multiple-indication reviews) and to highlight issues pertaining to such reviews. STUDY DESIGN AND SETTING MEDLINE was searched from 2003 to January 2014. We selected multiple-indication reviews of ...

A "mega-journal" is a new type of scientific journal that publishes freely accessible articles, which have been peer reviewed for scientific trustworthiness, but leaves it to the readers to decide which articles are of interest and importance to them. In the wake of the phenomenal success of PLOS ONE, several other publishers have recently started mega-journals. This article presents the evolut...

There has been much recent discussion about student engagement in higher education, and in the last few years a number of authors have undertaken extensive international research on the topic, which has been summarized in a number of literature reviews. However, to date, there has been relatively little in-depth exploration of student engagement in problem-based learning (PBL) or the impact of ...

Correction Following publication of our article [1], we became aware that the following disclaimer was missing: This project was funded under Contract No. HHSA290200710062I from the Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services. The authors of this report are responsible for its content. Statements in the report should not be construed as endorsement b...

Systematic reviews of the literature relevant to community-dwelling older adults are important to the practice of occupational therapy. We describe the four questions that served as the focus for the systematic reviews of the effectiveness of occupational therapy interventions for older adults living in the community. This article includes the background for the reviews; the process followed fo...

Context The RESTORE programme comprises a randomised controlled trial, three pilot trials, a cohort study, qualitative studies and systematic reviews. Since 2010, the patient panel (PEP-R), has inputted into RESTORE. Seventeen patients have been involved in total, 8 were recruited at the time of the evaluation. Through facilitated group sessions, PEP-R provides input into refinement of patient ...

An earlier paper in this series showed why systematic reviews are more reliable than other forms of review, such as the narrative commentary [1]. This paper takes this further by examining why systematic reviews which use individual patient data (IPD) are regarded as more reliable than other forms of systematic review [2]. It illustrates how the IPD approach can help achieve the ultimate aim of...

Cochrane systematic reviews are conducted and reported according to rigorous standards. A study flow diagram must be included in a new review, and there is clear guidance from the PRISMA statement on how to do this. However, for a review update, there is currently no guidance on how study flow diagrams should be presented. To address this, a working group was formed to find a solution and produ...