consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop. Arthritis Rheum 1999;42:1309–11. 2. Sanna G, Bertolaccini ML, Cuadrado MJ, Khamashta MA, Hughes GR. Central nervous system involvement in the antiphospholipid (Hughes) syndrome. Rheumatology 2003;42:200–13. 3. Brey RL, Abbott RD, Curb JD et al. Beta 2-glycoprot...

Twelve clinical trials have documented that prednisone or prednisolone in doses of 10 mg/day or less is efficacious to improve function, maintain status and/or slow radiographic progression in patients with rheumatoid arthritis (RA). An early trial reported by de Andrade et al. [Ann Rheum Dis 1964; 23: 158–162] in 1964 indicated that 5 mg of prednisolone at night was preferred to 5 mg of predni...

“General pronouncements on the significance of the plant acids are at present probably of little value. . . The true significance of the acid metabolism of plants may perhaps lie close to Kostytchev’s later point of view that these acids are the building stones from which some of the complex plant products originate. . . The plant acids are possibly convertible into amino acids and proteins, co...

Ziliang Ye,1 Shuang Zhang,1 Yuan Wang,1 Yong-Shik Park,1 Thomas Zentgraf,1 Guy Bartal,1 Xiaobo Yin,1,2 and Xiang Zhang1,2,* 1NSF Nanoscale Science and Engineering Center (NSEC), University of California, 3112 Etcheverry Hall, Berkeley, California 94720, USA 2Material Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA (Received 6 January 2012; revised manus...

graphic assessment of synovitis and joint vascularity with radiographic evaluation in randomized, placebo-controlled study of infliximab therapy in early rheumatoid arthritis. Arthritis Rheum 2004;50:1107–16. 7. Filippucci E, Farina A, Carotti M, Salaffi F, Grassi W. Grey scale and power Doppler sonographic changes induced by intra-articular steroid injection treatment. Ann Rheum Dis 2004;63:74...

'Rheum' comes from the Greek-a 'watery discharge' (OED)-and rheumatological literature as we scan it today has had two main historical sources for its now ever faster running river of words: (a) the spa waters and hydrology from the Middle Ages onward, beautifully illustrated in mediaeval woodcuts, and (b) the more modern mainstream of general medicine itself, even more widely and more strongly...

3. E. B. Thompson and M. E. Lippman, Metabolism 23, 9. A. G. Gornall, C. J. Bardawill and M. M. David, J. biol. 159 (1974). Chem. 177, 75 1 (I 949). 4. J. P. Binette and K. Schmid, Arth. and Rhrumat. 8, 14 (1965). 10. A. J. Collins and D. A. Lewis, Biochrm. Phurmac. 20, 251 (1970). 5. J. S. Lowe and E. H. Turner, Biochem. Pharmac. 22, 2069 (1973). 6. J. S. Lowe, Biochem. Pharmac. 13, 633 (1964)...