Background Carditis and rheumatic chronic heart disease are the most serious complications of Acute Rheumatic Fever. Nowadays prevention of recurrent episodes of group A b-hemolytic streptococcal pharyngitis is the most effective method to prevent the development of severe rheumatic heart disease. However the evidence of these guidelines are weak and result from studies conducted more than 50 y...

The incidence of rheumatoid factor in inflammatory disorders of connective tissue, particularly rheumatoid arthritis, has been discussed by Ziff (1957), Black, Goldin, Poske, and Malmed (1959), Bywaters, Carter, and Scott (1959), Kellgren and Ball (1959), Dixon (1960), and Hill and Greenbury (1965), and in other rheumatic and non-rheumatic diseases by Ziff (1957), Kellgren and Ball (1959), and ...

ONE of the most important steps in establishing the aetiology of any given disease is the production of similar specific lesions experimentally. In the case of rheumatic fever the precise causation has not yet been clearly shown, and preparatory to some experimental observations, it was decided to examine in some detail the lesions found in this condition. In the early days the presence of rheu...

The case presented is of a patient with migratory polyarthritis and serological evidence of a recent streptococcal infection, consistent with the diagnosis of acute rheumatic fever, who in addition had multisystem disease manifestations. This case supports the concept that the sequelae of streptococcal infection can encompass a broader clinical spectrum than is suggested by the Jones criteria f...

Serum immunoglobulin A (IgA) was markedly increased in 80% of 50 patients with acute rheumatic fever in Trinidad in contrast to 20% of 63 patients with acute glomerulonephritis, whereas serum IgG was increased in nearly all of both groups. Since total antibody to M-associated protein (MAP) (assessed by complement fixation) is the only antibody as yet consistently found to be of higher titer in ...

would be of use to know by pulsed Doppler echocardiography whether or not the origin of the murmur in question is consistent with a rheumatic process. When there has been no firm basis for the diagnosis of rheumatic fever, and pulsed Doppler echocardiography shows only a VSD, removal of the diagnosis of rheumatic fever and discontinuation of rheumatic fever prophylaxis may be considered. In cas...

BACKGROUND Acute rheumatic fever is considered a relatively uncommon disease in developed countries. Although cases are encountered in the Nazareth area in Israel, no systematic study of this disease has been done in the last 20 years. OBJECTIVE To study the incidence and characteristics of acute rheumatic fever cases in the Nazareth area during the last decade. METHODS Cases of acute rheum...

TmCLASSIC REPORT by Longsworth et at. (1) in 1939 on serum protein fractionation by free electrophoresis included rheumatic fever as one of the febrile diseases that had been studied. Employing the same medium, Rutstein et at. (2) followed this work with a more detailed study of serum proteins in rheumatic fever and noted changes in total protein and gamma globulin concentrations. Shetlar and c...