purpose: the aim of this study was to test the in vitro sensitivity of lymphocytes of patients with head and neck cancer against gamma irradiation and also to find out if the frequencies of chromosomal aberrations correlate with side effects of radiotherapy. patients and methods : peripheral blood of 101 patients with head and neck cancer was collected before the onset of radiotherapy, cultured...

In the further research and synthesis of highly bioactive 3-methylrhodanine derivatives, preparation benzylidene rhodanines followed by bicyclization to form pyrazole compounds has been undertaken. Using a convenient simple method, twelve have synthesized including six rhodanine derivatives ranging from good excellent yield, with four phenylhydrazone two at low yield. The structures all were el...

introduction: telomeric repeat amplification protocol assay (trap assay) is a standard established technique to detect the activity (expression) of telomerase in the cancerous samples. it includes a time-consuming procedure that has significant drawbacks such as high cost, complicacy, time-consuming procedure, equipment-dependent steps and false-positive signals caused by inclusion of pcr insid...