BACKGROUND Zoonotic cutaneous leishmaniasis is a growing health problem in many rural areas of Iran. Rhombomys opimus, the great gerbil, is the main animal reservoir of ZCL in the northeast and central part of Iran. The aim of the current study was to evaluate the rodenticidal effect of Coumavec® (a mixture of Coumatetralyl 0.5% and Etofenprox 0.5%) on R. opimus under laboratory condition. ME...

Applications of 0.29, 1.0, 2.63, and 5.26% strychnine-impregnated grain baits were applied below ground to 10' x 10' plots of alfalfa to determine translocation of strychnine from the soil to plants. Four replicates of each concentration were made and the alfalfa analyzed for strychnine residues. Four 10' x 10' plots were utilized as controls. Plant samples were taken on Day 1, Day 9, and Day 1...

The Caenorhabditis elegans sex-determination gene, tra-2, is translationally regulated by two 28 nt elements (DREs) located in the 3'UTR that bind a factor called DRF. This regulation requires the laf-1 gene activity. We demonstrate that the nematode Caenorhabditis briggsae tra-2 gene and the human oncogene GLI are translationally regulated by elements that are functionally equivalent to DREs. ...

Abstract Rats and mice can damage food agricultural products as well transmit diseases, thereby requiring control of their numbers. Application Second Generation Anticoagulant Rodenticides (SGARs) often reduces rodent numbers locally. However, predators eating rodents, including non-target species, that have consumed SGARs may be secondarily exposed potentially lethally poisoned. Here we study ...

Rodent populations particularly those that live in close proximity to man constitute a perennial and often severe threat to man's health as reservoirs and often as direct sources of infection for a wide variety of viral, rickettsial, and bacterial disease producing agents. The following will discuss the place of rodent population reduction for the control of plague, a bacterial disease of roden...

This paper discusses the development of site-specific baiting technology for controlling the house mouse (Mus musculus) in confined swine facilities utilizing specific rodenticide formulations, bait stations, and baiting strategies. Behavioral research was also conducted to identify primary nesting and travel activities of mice within grower-finishing units. The rodenticide bromadiolone in a bl...

The Columbian ground squirrel (Spermophilus columbianus), Richardson ground squirrel (Spermophilus richardsoni), and blacktail prairie dog (Cynomys ludovicianus) cause millions of dollars of loss to Montana agriculture each year. Montana's ground squirrel and prairie dog control programs are based upon local organization and operation with technical assistance being provided by the Montana Depa...

Carcinogenicity data of medicinal products for human use that have been authorised via the European centralised procedure (CP) between 1995 and 2009 were evaluated. Carcinogenicity data, either from long-term rodent carcinogenicity studies, transgenic mouse studies or repeat-dose toxicity studies were available for 144 active substances contained in 159 medicinal products. Out of these compound...