The authors’ present a silicon-on-insulator (SOI) laterally diffused metal-oxide-semiconductor field-effect transistor (LDMOSFET) with β-Ga2O3 , which is large bandgap semiconductor (β-LDMOSFET), for increasing breakdown voltage (VBR) and power figure of merit. fundamental purpose to use instead silicon material due its field. characteristics β-LDMOSFET are analysed those standard LDMOSFET, suc...

Epirubicin (EPI) is one of the most used intravesical chemotherapy agents after transurethral resection to non-muscle invasive bladder tumors (NMIBC) to prevent cancer recurrence and progression. However, even after resection of bladder tumors and intravesical chemotherapy, half of them will recur and progress. RON is a membrane tyrosine kinase receptor usually overexpressed in bladder cancer c...

This paper makes the case for Resilient Overlay Networks (RONs), an application-level routing and packet forwarding service that gives end-hosts and applications the ability to take advantage of network paths that traditional Internet routing cannot make use of, thereby improving their end-to-end reliability and performance. Using RON, nodes participating in a distributed Internet application c...

Lapatinib-resistance is a major problem for HER2-positive breast cancer treatment. SK-BR-3-LR, a lapatinib-resistant cell clone, was established from HER2-positive SK-BR-3 breast cancer cells following chronic exposure to lapatinib. The PI3K/AKT signaling pathway was demonstrated to be resistant to HER2 inhibition in SK-BR-3-LR cells. However, both small-molecular Recepteur d'Origine Nantais (R...

RON receptor tyrosine kinase is a proto-oncogene that induces cell migration and matrix invasion. RONΔ160 protein, which is produced by exclusion of exon 5 and 6, promotes cell migration, matrix invasion and protection from apoptosis. Alternative splicing regulation of exon 5 and 6 is not well understood. In this manuscript, we identified several new RNA regulatory elements for alternative spli...

Ron Mittler was born in Israel to a non-scientific family. He studied botany as an undergraduate at The Hebrew University of Jerusalem (BSc 1989) and eventually returned there to start his own research group after obtaining his PhD and gaining postdoctoral experience at Rutgers, The State University of New Jersey. In 2001 he moved his laboratory to the USA and spent time at Iowa State Universit...

At the start of my career, I had the good fortune of working with Ron Kaplan on Bill Woods’ Lunar system (Woods et al., 1972). One day, in talking with Ron, I marvelled to him over the range of syntactic constructions I was able to implement in Lunar’s ATN grammar formalism. Ron replied was that you could implement anything in an ATN: the point was, rather, to identify the minimal machinery req...

Abstract Fossil fuels still dominate future energy needs, while oil production has shown a declining trend over the past ten years. One solution to this condition is using new and renewable sources. In transportation sector, one of most common environmental problems resulting from combustion fossil in internal engines emission. Mixing gasoline with alcohol based on problem. This paper calculate...