BACKGROUND Tofacitinib, an oral Janus kinase inhibitor approved for the treatment of rheumatoid arthritis (RA), provides patients with an alternative to subcutaneously or intravenously administered biologic disease-modifying antirheumatic drugs (DMARDs). Little is known about patient preference for novel RA treatments. OBJECTIVE To investigate patient preferences for attributes associated wit...

BACKGROUND Influenza vaccines are recommended for administration by the intramuscular route. However, many physicians use the subcutaneous route for patients receiving an oral anticoagulant because this route is thought to induce fewer hemorrhagic side effects. Our aim is to assess the safety of intramuscular administration of influenza vaccine in patients on oral anticoagulation therapy. MET...

this study was performed to assess the incidence of medication errors and irrational use of human albumin in two wards of our hospital and also aimed to evaluate the ability of pharmaceutical care center and pharmacists in improving patient care. albumin administration was evaluated for patients who received albumin during the study period, in gastroenterology and general surgery wards. the ind...

Posterior subtenon injections of steroidal drugs are commonly used to treat various chorioretinal inflammatory diseases. Subsequent strabismus is rare, but it is associated with severe visual disturbance when present. We report a case of simultaneous bilateral inferior oblique muscle paresis in a 60-year-old man who developed it after receiving intravitreal injections of bevacizumab and posteri...

The pharmacokinetic studies of enrofloxacin were investigated in yak (Bos grunniens L.) after administration of enrofloxacin by intramuscular route at 5 mgkg-1 body weight. Blood samples were collected from the jugular vein at predetermined time intervals after drug administration. Plasma was separated and analysed for enrofloxacin by reverse-phase high performance liquid chromatography. Variou...

background: latrodectism, a syndrome caused by latrodectus genus, is one of the clinical problems that occur predominantly in north east of iran. nowadays antivenom therapy has become the most useful treatment for animal bites; however there is still a controversy about route and time of antivenom administration in spider bite. the aim of the present study was to determine the efficacy of speci...