Rubella is an acute, contagious viral infection caused by a teratogenic enveloped single-stranded RNA virus, rubella virus, a member of the togaviridae family. Though causing generally mild infections in children and adults, it is a disease of public health importance in pregnant women causing major problems including abortions, miscarriages, and congenital rubella syndrome in more than 20% of ...

Cerebrospinal fluid (CSF) and serum of 17 patients with HAM/TSP (HTLV-I associated myelopathy/tropical spastic paraparesis), six with multiple sclerosis and six with idiopathic epilepsy (non inflammatory control) from Brazil were analysed for the presence of intrathecal synthesis of virus-specific antibodies against measles, rubella, varicella zoster virus and herpes simplex virus by enzyme-lin...

during a period of 7 years (1997-2003) we were received pairs of serum and csf of 27 suspicious clinically cases from neurology department of several hospitals in tehran. among them 7 were serologically positive for progressive rubella panencephalitis (prpe) and 2 were positive for sub acute sclerosing panencephalitis (sspe). rubella virus was isolated from 4 of 7 serologically positive cases o...

OBJECTIVE To identify measles virus genotypes in three cases of travelers suspected of measles infection. METHODS Samples (blood and urine) were collected for serology, virus isolation, and genotyping. Sera were analyzed for IgM antibodies against measles virus and rubella virus by enzyme-linked immunosorbent assay (ELISA) (Siemens - Marburg, Germany). Clinical samples (lymphocytes and urine)...

BACKGROUND & OBJECTIVES Congenital rubella syndrome (CRS) accounts for a significant amount of mortality and morbidity in India. Rubella vaccination is not included in our national immunization programme. Occupational exposure of the health care personnel to rubella infection is well known. This study aims to assess the serological status of health care workers against rubella virus in Aravind ...

BACKGROUND Potency test for control of rubella vaccine is a significant factor to qualify production line and vaccination program. For this reason, WHO recommends to use the microtitration method by both vaccine companies and control laboratories. Then the study was done to improve this test. METHODS Three rubella virus samples, including an in-house standard, a lot of vaccine and an in-proce...

Ribonucleic acid (RNA) has been isolated from partially purified rubella virus preparations and fractionated by rate zonal centrifugation in sucrose density gradients. The bulk of the RNA sedimented as a sharp band with a sedimentation coefficient of 38S. Rubella virus RNA appears to be single-stranded on the basis of its sensitivity to the degrading action of ribonuclease. Fractionation by pre...

Circulating immune complexes which contained rubella-specific immunoglobulins were detected in 21 out of 63 subjects with congenital rubella and in 39 out of 65 subjects vaccinated with attenuated rubella virus, but in none of 43 subjects susceptible to rubella or 87 subjects with remote naturally acquired immunity to rubella. The presence or level of circulating immune complexes and the presen...

In 1971 Maurice Hillemanat at the Merck Institute of Therapeutic Research, a pharmaceutical company in West Point, Pennsylvania, created the measles, mumps, and rubella (MMR) vaccine. The vaccine combined three separate vaccines for measles, mumps, and rubella, common and sometimes fatal diseases. Measles causes a red skin rash and severe fevers that can be fatal. Mumps causes fever and swellin...

two hundred pa t ient s o f t he l ow socioe conomic g roup wi th an aborti on o f the f i r s t t r i mest e r were stud 1ed . the s ter i l e produc ts o f concept ion were c ul t ured on gr e e n monke y kidney ti s sue cul t ure f or v i r a l de t e c - tion. four po s i t i ve herpe s virus, two positive rubella v~ru s and t hree pos i tive unidentifie d entero v irus l ike vlrus were obt...