نتایج جستجو برای: s clavuligerus

تعداد نتایج: 711168  

Journal: :FEMS microbiology letters 2000
R Fouces M Rodríguez E Mellado B Díez J L Barredo

The tlrB gene from Streptomyces fradiae has been cloned and used to construct bifunctional Streptomyces-Escherichia coli shuttle vectors carrying the antibiotic resistance genes to kanamycin-neomycin, thiostrepton and tylosin as selection markers. In the same way, the tlrB gene was subcloned in plasmids including the apramycin resistance gene and the oriT sequence from the plasmid pSET152 to fa...

Journal: :Journal of bacteriology 1997
F Pérez-Llarena J F Martín M Galleni J J Coque J L Fuente J M Frère P Liras

A gene (bla) encoding a beta-lactamase is present in the cephamycin gene cluster of Streptomyces clavuligerus, the strain producing clavulanic acid and a beta-lactamase inhibitory protein. The bla gene is located 5.1 kb downstream from and in the opposite orientation to cefE, encoding the deacetoxycephalosporin C synthase. The bla gene encodes a 332-residue protein (Mr, 35,218), similar to othe...

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