Efficient drug delivery to target tissue is a major challenge in many cancer treatment modalities. Silica nanoparticles (SiNPs) have been identified as an ideal carrier due their unique properties. In Photodynamic therapy (PDT), one of the key challenges utilizing photosensitizers (PS) lies effectively delivering PS targeted tissue. Using encapsulation will prevent leakage entrapped from partic...

Penggunaan safranin memiliki kelemahan yaitu harganya yang mahal serta warnanya sulit terserap pada preparat tertentu. pewarna alami merupakan alternatif untuk menggantikan . Salah satu dapat digunakan adalah air rendaman angkak dan daun jati. Penambahan oksidator alam menghasilkan lapang pandang bersih bentuk bakteri sempurna. Tujuan penelitian mengetahui pengaruh penambahan jati terhadap modi...

Silk-based scaffolds have been introduced to bone tissue regeneration for years, however, their local therapeutic efficiency in bone metabolic disease condition has been seldom reported. According to our previous report, mesoporous bioactive glass (MBG)/silk scaffolds exhibits superior in vitro bioactivity and in vivo osteogenic properties compared to non-mesoporous bioactive glass (BG)/silk sc...

Genes (ebrAB) responsible for ethidium resistance were cloned from chromosomal DNA of Bacillus subtilis ATCC 9372. The recombinant plasmid produced elevated resistance against ethidium bromide, acriflavine, pyronine Y, and safranin O not only in Escherichia coli but also in B. subtilis. It also caused an elevated energy-dependent efflux of ethidium in E. coli. EbrA and EbrB showed high sequence...

The aim of this study was to verify the occurrence of Cryptosporidium infection in 52 human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients (group 1) and 38 clinically healthy individuals (group 2) by using enzyme immunoassay (EIA). All fecal samples collected were submitted to the Baermann, Lutz and Ritchie methods, the Safranin/Methylene Blue, and Weber's chrom...

Unequivocal evidence of the viral nature of virus-like particles observed at the specific site of retention of tobacco rattle virus (TRV) in Paratrichodorus and Trichodorus nematodes has not previously been available. A new staining technique using safranin-O, which does not affect viral antigenicity, was used with an antiserum raised against the coat protein of TRV and prepared for use with im...

The objectives of this study were to evaluate the antimicrobial capacity photosensitizer (PS) safranin-O (Sf), through photodynamic therapy (PDTa), against strains Pseudomonas fluorescens (PV1, PVh, and PC3) Staphylococcus aureus (SV1, SV3, SV5, SC5, SC6, SC8) isolated from milk cows goats biofilm formation on equipment. To effectiveness formulation, studies carried out in situ applications Sf ...