BACKGROUND AND PURPOSE Preoperative prediction of tumor malignancy is clinically very important, because this information strongly influences the surgical plan. We evaluate the preoperative apparent diffusion coefficient (ADC) maps of benign and malignant salivary gland tumors. MATERIALS AND METHODS High-resolution MR imaging was performed on 31 patients with benign or malignant salivary glan...

The studies described in this thesis were carried out at the departments of Oral and Contents Chapter 1: General Introduction 9 Chapter 2: Variations in mucins and mucin-associated carbohydrate 25 antigens expression in mucoepidermoid carcinomas Chapter 3: High number of chromosomal copy number aberrations 43 inversely relates to t(11;19)(q21;p13) translocation status in Mucoepidermoid Carcinom...

OBJECTIVES PD-1/PD-L1 and CTLA-4 have been investigated and are thought to play an important role in tumor evasion. This study aimed to investigate expression patterns of immune-related molecules, and their clinical impacts in malignant salivary gland tumors. PATIENTS AND METHODS We performed immunohistochemical staining for PD-L1, PD-L2, CTLA-4, PD-1, and CD8+ tumor-infiltrating lymphocytes ...

PAX2 and PAX8 are transcription factors involved in embryogenesis that have been utilized as immunohistochemical indicators of tumor origin. Specifically, PAX2 is a marker of neoplasms of renal and müllerian origin, while PAX8 is expressed by renal, müllerian, and thyroid tumors. While studies examining these transcription factors in a variety of tumors have been published, data regarding their...

Salivary gland carcinomas are rare tumors, representing ~0.5% of all malignancies. Myoepithelioma is also uncommon, representing ~1% of all salivary gland tumors. Myoepithelial carcinoma (MC) is even rarer, representing 0.2 to 0.6% of all salivary gland tumors. We herein report a case of MC with multiple metastases arising from a submandibular gland in a 71-year-old male patient and present the...

Salivary gland tumors are uncommon, the world wide annual incidence of salivary gland tumors ranges from 0.4 to 13.5 cases per 100 000 population (Auclair et al., 1991). Tumors of salivary glands account for 2% to 6.5 % of head and neck neoplasms and 21% to 46% are malignant (Ellis & Auclair, 1996). In Bangkok, during the period 2001-2003, the estimated age standardized incidence rate of saliva...

AIM To describe demographic and histomorphological characteristics of 139 patients with epithelial salivary gland tumors in the Southeastern Serbia population. METHODS A total number of 139 patients with epithelial tumors arising in major and minor salivary glands in the period 2010-2012 was evaluated. After standard tissue proceeding, the routine haematoxylin-eosin (HE) and histochemical alc...