Background: Metabolic syndrome translates into a higher risk of developing diabetes or cardiovascular disease due to insulin resistance among these patients. Osteocalcin, bone-derived protein secreted by osteoblasts, decreases blood glucose, novel mechanism. It increases the secretion adiponectin, and stimulates production endogenous insulin. Increased serum osteocalcin levels have positive imp...

OBJECTIVE: Oral manifestations in diabetic patients can have different causes. Possibly, one of these causes is salivary glucose. The aim of this study was to evaluate salivary glucose concentrations in patients with Type II diabetes mellitus (DM) and their association with oral and dental manifestations and compare them with normal adults. MATERIALS AND METHODS: In this analytical study, 128 p...

Background: This study was performed to evaluate the effects of probiotics on salivary flow rate and pH in children with Acute Lymphocytic Leukemia (ALL) during chemotherapy.   Methods: A randomized clinical trial was conducted on 11 children with ALL on induction and consolidation phases of chemotherapy. At the beginning, clinical examination of the oral mucosa and dental hygiene and intervie...

OBJECTIVE To examine the relationship between Zn nutritive status and biochemical markers of bone turnover in type 1 diabetes. RESEARCH DESIGN AND METHODS Serum osteocalcin, urine N-telopeptides, and dietary intake data, obtained by 3-day food records, were assessed for 66 individuals with type 1 diabetes. RESULTS Zn intake correlated with osteocalcin in the group overall (r = 0.48; P < 0.0...

BACKGROUND Osteocalcin is a hormone with a complex cross-talk between adipose tissue and the skeleton. The aim of the present study was to explore the relation of osteocalcin with histopathological changes of NALFD patients. SUBJECTS A population of 69 NAFLD patients was analyzed. A liver biopsy was realized. Weight, fat mass, body mass index, basal glucose, insulin, insulin resistance (HOMA)...

Osteoporosis and atherosclerosis often present atypically in postmenopausal women, making clinical recognition difficult. Prospective studies suggest independent associations between bone mass and vascular calcification through vitamin D deficiency as an established predictor of both conditions. We aimed to examine the relationship between serum osteocalcin and vitamin D status in postmenopausa...

Purpose Herein we evaluated the effects of platelet concentrate (PC) and platelet-poor plasma (PPP) on bone repair using noncritical defects in calvaria rabbits compared them to presence TGF-β1 osteocalcin reparative sites. Methods Five 8.7 mm diameter were created 15 animals. Each defect was treated differently, autograft (ABG), ABG associated with PC (ABG + PC), PPP PPP), isolated PPP, blood ...

Objective: Osteocalcin has been shown to exert an endocrine influence on bone and energy metabolism in both animals and humans; recent evidence indicating a regulatory role for osteocalcin in glucose homeostasis and energy metabolism and as a marker for bone metabolism. The aim of this study was to investigate the interaction between osteocalcin, body composition, and blood biomarkers in men wi...

OBJECTIVE Bone mineral density has been reported to negatively associate with nonalcoholic fatty liver disease. Osteocalcin, a bone formation marker and metabolic regulator, has been previously evaluated as the mediator between bone mineral density and nonalcoholic fatty liver disease. Herein, we aimed to investigate the correlations of nonalcoholic fatty liver disease with bone mineral density...