Salmonellosis outbreaks involving typhoid fever and human gastroenteritis are important diseases in tropical countries where hygienic conditions are often not maintained. A rapid and sensitive method to detect Salmonella spp., Salmonella Typhi and Salmonella Typhimurium is needed to improve control and surveillance of typhoid fever and Salmonella gastroenteritis. Our objective was the concurren...

Salmonella enterica serovar Typhi is the causative agent of typhoid fever, which causes nearly 21.7 million illnesses and 217,000 deaths globally. Herein, we describe the whole-genome sequence of the Salmonella Typhi strain ST0208, isolated from a sporadic case of typhoid fever in Kuala Lumpur, Malaysia. The whole-genome sequence and comparative genomics allow an in-depth understanding of the g...

Sepsis due to Salmonella enterica serovar Typhi and Paratyphi A is rare in neonates. Though described as a mild and unrecognized illness in infants, life-threatening complications and even deaths have been reported. We present five cases of neonatal septicaemia due to S. Typhi and S. Paratyphi A. The cases were presented because of their interesting clinical presentations and possible modes of ...

Salmonella enterica subsp. enterica serovar Typhi is a human-restricted pathogen that causes typhoid fever. Even though it is a human-restricted pathogen, the bacterium is also isolated from environments such as groundwater and pond water. Here, we describe the genome sequence of the Salmonella enterica subsp. enterica serovar Typhi PM016/13 which was isolated from well water during a typhoid o...

A saline vaccine prepared from our stock strain of M. T. II produces in mice definite protection against the homologous strain, and perhaps some slight cross-protection against M. T. I also. Two vaccines prepared with our stock strain of M. T. I failed to produce any definite protection in mice even against the homologous strain, nor was any cross-protection afforded against M. T. II.

The use of 10% oxgall and bile broth medium, both supplemented with freshly prepared 100 u/ml streptokinase, for isolating Salmonella typhi by clot culture technique was evaluated and compared against whole blood culture systems (3 ml blood in 9 ml media and 8 ml blood in 72 ml media). These gave a 1:4 and 1:10 blood to medium ratio, respectively. Clot cultures in 10% oxgall (CLOX) gave a 57% p...

Salmonella typhi usually produces enteric fever and gastroenteritis. The infection may spread through blood stream and present as local suppurative lesions which may involve any site including the bone and joints. We report a case of septic arthritis of hip in a patient with systemic lupus erthematosis. The case is presented for its rarity and to highlight the atypical manifestations of Salmone...

Typhoid fever is becoming an ever increasing threat in the developing countries. We have improved considerably upon the existing PCR-based diagnosis method by designing primers against a region that is unique to Salmonella enterica subsp. enterica serovar Typhi and Salmonella enterica subsp. enterica serovar Paratyphi A, corresponding to the STY0312 gene in S. Typhi and its homolog SPA2476 in S...

background and objectives: annual incidence of infection with s. typhi is estimated to be about 17 million cases worldwide. a systematic search among actinomycete isolates from soil of iran aimed at finding active actinomycetes against the causative agent of typhoid fever, salmonella typhi was carried out during this study. materials and methods: our anti- salmonella screening program resulted ...

The common histopathologic hepatic manifestations in patients infected with Salmonella include cloudy swelling and balloon degeneration with vacuolation of the hepatocytes and steatosis. Hepatic granulomas are a very rare finding, so far reported in very few cases. We report a 64-year-old patient with Salmonella enteritis who was found to have multiple 1.4 to 1.6 cm hypoechoic liver masses on u...