BACKGROUND Potassium-enriched diets exert renal and cardiovascular protective effects, but the underlying mechanisms are largely unknown. METHODS Using the dorsal skinfold chamber model for intravital microscopy, we examined endothelium-dependent vasorelaxation of precapillary resistance arterioles in response to acetylcholine or the NO donor SNAP in awake mice. Experiments were performed in ...

Cellular memory of past experiences has been observed in several organisms and across a variety of experiences, including bacteria "remembering" prior nutritional status and amoeba "learning" to anticipate future environmental conditions. Here, we show that Saccharomyces cerevisiae maintains a multifaceted memory of prior stress exposure. We previously demonstrated that yeast cells exposed to a...

1. The resistance of erythrocytes of dogs to the hemolytic activity of cobra venom is increased after splenectomy. 2. This increased resistance was observed as early as 4 days after splenectomy and usually persisted for a period of about 3 weeks, when the resistance gradually decreased to normal or slightly beyond. 3. The decrease of resistance to the hemolytic activity of venom for the erythro...

The PEX11 family of peroxisome membrane proteins have been shown to be involved in regulation of peroxisome size and number in plant, animals, and yeast cells. We and others have previously suggested that peroxisome proliferation as a result of abiotic stress may be important in plant stress responses, and recently it was reported that several rice PEX11 genes were up regulated in response to a...

We used a cell-free, 5% albumin-containing bicarbonate saline solution to perfuse kidneys of salt-sensitive (S) and salt resistant (R) rats derived from Dahl's original strains. The animals had been maintained on diets whose salt content was either 8% ((+)Na) or 0.4% ((-)Na). On these regimens only S(+)Na rats become hypertensive. Glomerular filtration rate (GFR), urinary sodium excretion (NaE)...

the objective of this experiment was to determine the effects of different levels of nitrogen (n) and salinity on biochemical mechanisms of two wheat genotypes. a field experiment was carried out in a three replicate rcbd split factorial experiment in salinity station of college of agriculture, ferdowsi university of mashhad, iran in 2007-2008 and 2008-2009. three levels of salt stress (1.3, 5,...

Serotonin (5-hydroxytryptamine; 5-HT) delivered over 1 week results in a sustained fall in blood pressure in the sham and deoxycorticosterone acetate (DOCA)-salt rat. We hypothesized 5-HT lowers blood pressure through direct receptor-mediated vascular relaxation. In vivo, 5-HT reduced mean arterial pressure (MAP), increased heart rate, stroke volume, cardiac index, and reduced total peripheral ...

BACKGROUND AND AIMS Different populations of the Mediterranean xerohalophyte species Atriplex halimus exhibit different levels of resistance to salt and osmotic stress depending on the nature of the osmocompatible solute they accumulate. There is, however, no conclusive description of the involvement of abscisic acid (ABA) in the plant response to NaCl or osmotic stress in this species. METHO...