Abstract: SAPHO syndrome is characterized with a set of symptoms including skin lesions, osteoarticular manifestations like aseptic osteitis (of the anterior chest wall or other skeletal sites), peripheral synovitis. Due to lack randomized clinical trials and low prevalence condition, there are no established treatment guidelines for syndrome. Here, we report case sternum palmoplantar pustulosi...

Purpose: Demonstrate the possible manifestations of SAPHO syndrome. Material and methods: 38-year-old woman with suspected syndrome were performed scintigraphy SPECT/CT for evaluate localization abundance process. Results: Osteosclerosis hyperostosis left clavicle, osteosclerosis L1 vertebra other, less pronounced changes, accompanied by active accumulation 99mTc-MDP, revealed. Conclusion: It i...

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) is a relatively rare often underdiagnosed disorder characterized by chronic inflammation affecting the bones, joints, skin. While precise cause of SAPHO syndrome remains elusive, multiple factors such as genetics, immunological dysregulation, bacterial influences have been implicated in its pathogenesis. One notable aspect wide var...

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, a rare disorder with spectrum of manifestations overlapping osseous cutaneous symptoms, shares pathogenesis various autoimmune diseases. SARS-CoV-2 has been previously linked to diseases like Guillain-Barré syndrome (GBS), multi-inflammatory in children (MIS-C), or rheumatoid arthritis, but there is no existing work showi...