Background: Reaching the differential diagnosis of tuberculosis and sarcoidosis can be difficult due to granulomatous inflammation. The aim of this study was to determine alkaline phosphatase (ALP) activity in serum for the differential diagnosis of tuberculosis and sarcoidosis. Methods: This study comprised 242 subjects: 105 acid-fast bacilli (AFB) positive and/or culture-positive patients wit...

Lung transplantation (LT) is an appropriate therapeutic option for patients with severe, fibrocystic pulmonary sarcoidosis refractory to medical therapy. Survival rates following LT for sarcoidosis are generally comparable to other indications. Timing of transplantation for patients with sarcoidosis is challenging because mortality rates are high (27 to 53%) among sarcoid patients awaiting LT. ...

BACKGROUND The possible association between (tuberculous and nontuberculous) mycobacterial infections and sarcoidosis is still a matter of dispute. Using diagnostic tests for specific T-cell responses, this association can be investigated in an innovative manner. OBJECTIVE To measure the T-cell responsiveness to the purified protein derivative (PPD) antigen in blood and broncho-alveolar lavag...

BACKGROUND AND AIM OF THE WORK The causes of sarcoidosis are still unknown. Propionibacterial subspieces are thought to be one of the most likely sources of antigens. Here we attempted to measure the amount of propionibacterial DNA in bronchoalveolar lavage (BAL) cell samples from patients with sarcoidosis and other pulmonary diseases. METHODS We examined BAL cells from 42 patients with sarco...

The simultaneous presence of hematological malignancies and sarcoidosis, defined as sarcoidosis-lymphoma syndrome, has been reported in 79 patients in the literature to date. The majority of these patients were affected by sarcoidosis and developed non-Hodgkin lymphoma or acute leukemia after 1-2 years; however, in <20 cases the malignancy developed first. This report presents the case of an 83...

CONTEXT Symptomatic pancreatic involvement in sarcoidosis is extremely rare. There are 25 reported cases of detected pancreatic sarcoidosis before death. CASE REPORT We report the case of a male patient with a history of pulmonary sarcoidosis, who presented with clinical picture and CT scan findings suggestive of pancreatic cancer. Pancreatic mass biopsy showed lesions consistent with sarcoid...

with sarcoidosis usually preceding lymphoma. Because many features of sarcoidosis and lymphoma are similar, histological confirmation of malignancy is necessary, especially if new nodal disease and splenomegaly are present. Sarcoidosis, although rare, may complicate the course of lymphoma. Prominent features of sarcoidosis were respiratory symptoms, high ACE levels, BHL in asymptomatic subjects...

Sarcoidosis is a granulomatous disease of unclear etiology. Cardiac involvement in sarcoidosis is rarely diagnosed clinically. It is not commonly fatal, but when sarcoidosis is fatal, it is most often from cardiac involvement and when sarcoidosis involves the heart, it frequently causes death. We report a case of sudden death of 48 years male, wherein sarcoidosis with cardiac involvement was di...

We report on a case of the so-called sarcoidosis-lymphoma syndrome in a 65-years-old man diagnosed as having sarcoidosis and, four years later, neurosarcoidosis. The diagnoses of epidermoid carcinoma of the skin and of stage IV monocytoid, small cell lymphocytic lymphoma were made five and seven years, respectively, after the initial diagnosis of sarcoidosis. It has been suggested that the incr...

Sarcoidosis is a multisystem disease which is most commonly manifested in the pulmonary system. However, extrapulmonary manifestations have also been frequently reported. Isolated occurrence of sarcoidosis in the genital system is rare and poses a diagnostic and therapeutic dilemma. Uterine sarcoidosis can present with cervical erosions, endometrial polypoid lesions, and recurrent serometra. In...