The in vitro effects of the toxin coumarin compounds scopoletin and aflatoxin B1 (AFB1) on bovine (Bos indicus) hepatic mitochondrial respiratory complex III enzymes, succinate cytochrome c and a-ketoglutarate cytochrome c reductases, were examined. Kinetic studies on the interaction of the toxins with the enzymes were also carried out. The results showed that although the observed inhibitory a...

In this recent study, several trials were made to develop a HPTLC method for quantification of scopoletin and piperine in the Ajmodadi formulation. was done on pre-coated silica gel 60 F254 plates with mobile phase toluene:ethyl acetate:methanol:formic acid (3.9:3.9:0.3:1.7 v/v/v/v). The retardation factors 0.75 0.86 found good defined resolution peak. Densitometer analysis carried out at 335 w...