BACKGROUND Direct measurement of glomerular filtration rate (GFR) is the preferred method to assess renal function in cats, but it is not widely used in the diagnosis of chronic kidney disease (CKD). In cats with CKD, symmetric dimethylarginine (SDMA) has been shown to increase and to correlate with plasma creatinine concentrations. HYPOTHESIS In cats, reduced GFR corresponds with increased s...

BACKGROUND Plasma creatinine concentration and calculated creatinine clearance are of limited value as glomerular filtration rate (GFR) markers in patients with decompensated liver cirrhosis. We assessed plasma cystatin C as an indicator of GFR in such patients. METHODS We studied 36 patients with decompensated liver cirrhosis and 56 noncirrhotic controls, both groups including individuals wi...

The aim of this study was to predict urinary creatinine excretion (UCr), creatinine clearance (CCr) and the glomerular filtration rate (GFR) from body composition analysis. Body cell mass (BCM) is the compartment which contains muscle mass, which is where creatinine is generated. BCM was measured with body impedance analysis in 165 chronic kidney disease (CKD) adult patients (72 women) with ser...

AIMS To evaluate the quality of bedside estimation of glomerular filtration rate (GFR) in hospitalized elderly patients. METHODS We evaluated common estimators of GFR in 29 women and 32 men aged 60 and older hospitalized in a geriatric ward: creatinine clearance (CCR), the Cockcroft-Gault formula (CG), the modification of diet in renal disease formula (MDRD), Baracskay formula (BAR), and a ne...

OBJECTIVE To compare performance of combined creatinine and cystatin C-based equation with equations based on either cystatin C or creatinine alone, in early chronic kidney disease. DESIGN Diagnostic accuracy study. SETTING Tertiary-care hospital. PATIENTS One hundred children with chronic kidney disease who underwent 99mTc diethylenetriamine pentaacetic acid (DTPA) glomerular filtration ...

To evaluate renal functions in camel, the study on profiles like Serum Creatinine (SC), Serum urea nitrogen (SUN), SUN/SC ratio was undertaken in institute’s herd of camels (n=250) (Camelus dromedarius) of all age groups, both sexes and three breeds and in addition Glomerular Filtration rate (GFR) of 18 male camels of 3 breeds (n=6 each) with 6 individual replicates (Total 108 observations) wer...

OBJECTIVE To validate glomerular filtration rate (GFR) estimating equations in white HIV-infected patients based on serum creatinine and/or serum cystatin C. DESIGN Single-center, cross-sectional evaluation of the predictive performance of GFR estimators. METHODS GFR was measured by iohexol plasma clearance. Serum creatinine (Scr) and serum cystatin C (Scyst) were measured by traceable and ...

BACKGROUND We aimed to evaluate the performance of serum cystatin C-based equations in calculating the glomerular filtration rate (GFR) in patients with varying stages of chronic kidney disease (CKD). METHODS Serum cystatin C and creatinine levels were measured in 615 CKD patients. The CKD stage was determined by the creatinine-based estimated GFR (eGFR) equation using the four-variable abbre...

Schwartz et al. (1 ) have reported a new formula for estimating the glomerular filtration rate (GFR) in children with chronic kidney disease (CKD). This is an excellent analysis based on a carefully described, prospectively recruited cohort of children with various types of kidney diseases that have compromised function. The analysis is precise and the results seem to provide a more accurate, n...

Background: Hypertension is one the most common causes of chronic kidney disease (CKD). One of the major concerns in hypertensive patients is early detection of renal disorders. In the past, serum creatinine (Scr) concentration was used as a marker of kidney function, but it proffers a late reflection of reduced glomerular filtration rate. Cystatin C and neutrophil gelatinase-associated lipocal...