BACKGROUND This paper aimed to verify the effects of renal replacement therapy on changing the levels of serum creatinine for different veno-arterial and veno-venous configurations in prolonged extracorporeal membrane oxygenation (ECMO) patients. METHODS The subjects were chosen 71 patients who had undergone more than 1,440 minutes (24 hours) of the therapy from among 117 patients who had und...

BACKGROUND Skeletal muscle is well established as a major target organ of insulin action, and is associated with the pathogenesis of type 2 diabetes. Therefore, we attempted to determine whether a variation in serum creatinine is related to the development of type 2 diabetes and other risk factors for diabetes. METHODS A total of 2,676 nondiabetic subjects with stable and normal renal functio...

Purpose: To investigate the dual effect of angiotensin blockade by irbesartan and enalapril on proteinuria in diabetic patients with azotemia. Methods: Patients with diabetes of > 5 years duration, proteinuria at a nephrotic level and serum creatinine > 1.5 mg/dL were enrolled in the study. Forty-five enrolled patients were divided into three groups, those receiving enalapril , irbesartan, or e...

background: contrast nephropathy will increase mortality up to 30% following angiographic procedures. adenosine is a crucial mediator of contrast-induced nephropathy. the purpose of this study was to investigate whether the adenosine antagonist theophylline reduces the incidence of cn after coronary angiography. methods: in this randomized, double-blind, placebo-controlled clinical trial study,...

Results Mean age was 52 ± 12 years. In-hospital peri-operative mortality was 12.9%. Mean aortic cross-clamp time was 124 ± 72 minutes; mean duration of deep hypothermic circulatory arrest (DHCA) was 47 ± 30 minutes. 25.8% of patients developed post-operative acute kidney injury. 6.5% required temporary renal replacement therapy. Preoperative renal impairment and presence of ischemic heart disea...

Concentration of serum cystatine C primarly dependes on the glomerular filtration rate (GFR), and cystatin C concentration in serum can be used as an endogenous marker of kidney function. Use of cystatin C in the assesment of GFR in elderely, childern and pre dialysis patients could be usful. The aim of the study was to evaluate the use of cystatin C as a renal marker of the glomerular filtrati...

The renin-angiotensin system is involved in the progression of chronic renal disease of both diabetic and nondiabetic origin. The angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers have been demonstrated to reduce urinary protein excretion and attenuate the development of renal injury. This prospective, randomized, 12-month study assessed the effects of ramipril (N = ...

Background: Accurate and rapid assessment of allograft function is essential in renal transplant recipients in order to detect allograft rejection and to monitor drug nephrotoxicity. We aimed to evaluate the usefulness of cystatin C as a marker of kidney allograft function in the early post-transplant period and to compare this value with that of conventional serum creatinine concentration. Met...

Objective: A significant negative association between serum thyroxine and urine perchlorate levels had been reported from NHANES 2001-2002 by Blount et al. (2006) for women age 12-85 with low iodine nutrition expressed as urine iodine (UI) less than 100 ug/l. We have reanalyzed the data using creatinine-adjusted urine iodine (UICr) as the measure of iodine nutrition and focused on women of chil...

Objective: Diabetes mellitus is a multifactorial metabolic disorder that affects multiple organs of the body, one of the most important of which is chronic kidney disease. Early diagnosis of this disease is suggested as an important strategy to reduce the complications of the disease worldwide. Since the measurement of salivary creatinine and glucose is an easy and noninvasive method, the aim o...