OBJECTIVES To analyse the effect of zinc supplementation in growth and nutritional status of a homogeneous group of newborns with intra uterine growth retardation and asymmetric growth. The effect of changes of zinc status on growth and leptin serum concentrations was also analysed. POPULATION AND METHODS A double blind, randomised clinical trial was designed in order to detect differences in...

1. Distribution of zinc between the metalloprotein alpha 2-macroglobulin and albumin was determined in samples of serum obtained from twenty-three women in their third trimester of pregnancy and eighteen women who were not pregnant. 2. The decrease observed in total serum zinc in the group of pregnant women could be accounted for in large part by a decreased concentration of albumin-bound zinc....

background: adequate serum level of zinc and selenium is required for normal metabolic performance and successful fertility. the present study was conducted to evaluate the association of serum zinc and selenium in early stage of gestation with the incidence of miscarriage in iranian women. materials and methods: one hundred two females were studied in three matched groups. group 1 consisted of...

BACKGROUND There is some evidence coming from preclinical and clinical studies suggesting a relationship between dietary zinc intake and depressive symptoms. The aim of the study was to determine whether zinc deficiency alters the response to antidepressants with a different mechanism of action. We examine also whether these changes are related to activity of the hypothalamic-pituitary-adrenal ...

We examined the distribution of zinc in the periphery (erythrocytes and serum) in a large, well-characterised cohort, the Australian Imaging, Biomarkers and Lifestyle (AIBL) study, in order to determine if there is systemic perturbation in zinc homeostasis in Alzheimer's disease (AD). We observed an age dependent decrease in serum zinc of approximately 0.4% per year. When correcting for the age...

BACKGROUND Some children with congenital heart diseases (CHD) may have increased pulmonary blood flow that causes recurrent bronchopneumonia and congestive heart failure. Serum zinc is reduced in children with pneumonia and patients on diuretics. OBJECTIVE To evaluate the serum zinc level of children with CHD and their controls without CHD. METHOD The subjects were 41 children with CHD conf...

BACKGROUND Zinc is an essential trace element with a prominent role in human nutrition. Zinc deficiency has been linked to growth retardation, hypogonadism in males, and lack of sexual development in females. It ranges from 50% in sub-Saharan Africa to 5% in high income countries. The aim of this study is to evaluate the prevalence of zinc deficiency in healthy children in Shiraz, southern Iran...

Many studies have investigated the association between serum/hair zinc levels and breast cancer, but the results were inconsistent. To compare the serum and hair zinc levels in women with breast cancer and controls, we conducted a systematic literature search of PubMed, Web of Science, Cochrane Library and Embase to identify relevant studies with publication dates up through November 2014. Base...

The activity in serum of zinc-dependent angiotensin converting enzyme (ACE), is measured to aid in diagnosis and monitor treatment of certain diseases. This report shows the effect of dietary zinc deprivation on ACE activity in the serum of rats. The mean (and SE) of the zinc concentration (mumol/L) in serum was 3.5 (0.3) in rats deprived of dietary zinc for four days, 16.3 (0.2) in control rat...

The association between serum zinc level and preeclampsia (PE) remains controversial. A systematic literature search was performed in PubMed, Web of Science and Embase for relevant available articles. The articles were limited to those in English from January 1990 to April 2015. Observational studies evaluating the association between serum zinc level and PE were included. The I² was used to as...