Myocardial injury is common in patients with coronavirus disease 2019 (COVID-19). Among COVID-19 related myocardial injuries, etiology may vary, including myocarditis, infarct, sepsis-associated injury, and/or stress-induced cardiomyopathy. More data from prospective cohorts and case series are needed to understand the exact mechanism of associated injuries. It clinically suspected that myocard...

BACKGROUND Middle East Respiratory Syndrome coronavirus (MERS-CoV) is a viral respiratory disease. Most people infected with MERS-CoV develop severe acute respiratory illness. It was first reported in Saudi Arabia in 2012 and has since spread to several other countries. We report the clinical course of MERS-CoV infection in a pregnant woman who acquired the infection during the last trimester. ...

The world was brought to a standstill by the rapid spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), responsible for COVID-19. Initially recognized in Wuhan, China, December 2019, it announced be pandemic. It is known from person via respiratory droplets such as saliva, cough and sneeze

The FDA is developing guidance for manufacturers of diagnostics, therapeutics, and vaccines to aid their response emerging severe acute respiratory syndrome coronavirus 2 variants, Acting Commissioner Janet Woodcock, MD, said in a statement.

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a major global concern. As of writing this manuscript, there are over 224 million cases diagnosed with the coronavirus disease 2019 (COVID-19) and 4.5 million recorded deaths by the disease. Objectives: This review article investigates studies conducted on SARS-CoV-2 pathogenesis, transmission, and different cl...

The severe acute respiratory syndrome (SARS) coronavirus 3CL protease is an attractive target for the development of anti-SARS drugs. In this paper, cinanserin (1) analogs were synthesized and tested for the inhibitory activities against SARS-coronavirus (CoV) 3CL protease by fluorescence resonance energy transfer (FRET) assay. Four analogs show significant activities, especially compound 26 wi...