Keywords: Polycystic ovarian syndrome PCOS Anti-mullerian hormone AMH PCOD Original Article Polycystic ovarian syndrome is a complex heterogeneous disorder of unknown etiology and shows mild to severe degree of signs and symptoms affecting the reproductive, endocrine and metabolic functions. Anti-mullerian hormone, a dimeric glycoprotein belonging to the transforming growth factor–beta superfam...

AIMS To examine the associations between endogenous sex steroid hormones (oestradiol, testosterone and sex hormone-binding globulin) with diabetes risk in a South-Asian population living in the USA. METHODS We used data from the Metabolic Syndrome and Atherosclerosis in South-Asians Living in America pilot study. The analytical sample included 60 women and 45 men of Asian Indian origin living...

BACKGROUND To date, there are limited studies on the sex-specific relationship between fetuins (Ft-A and Ft-B) and metabolic diseases. Our recent proteomic study has shown that fetuins may play sex-dependent roles in obesity and diabetes. In the present study, we investigated the expression of hepatic fetuins with respect to the effects of sex hormones both in vivo and in vitro. METHODS & RES...

In this study, we examined the relationship between sex hormone levels and lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH) who underwent transurethral surgery. The study was conducted in 158 patients who came to our hospital for surgery. Clinical conditions were assessed by body mass index (BMI), digital rectal examination, International Prostate Symptom Score...

It has been suggested that the amount of maternal testosterone allocated into the eggs might be implicated in the process of sex determination. However, recent findings on the effect that female social rank has on the level of egg testosterone suggest that reported associations between male-biased sex ratios and yolk testosterone may represent an indirect hormonal effect mediated by the interde...

OBJECTIVE A sex determining gene(s) has been mapped to a approximately 700 kb region distal to the exons of DMRT1 on 9p. The aim of this study was to examine gonadal developmental status in XX patients hemizygous for the 9p sex determining region. DESIGN Clinical and molecular studies were performed in an 8-year-old girl with 46,XX,del(9)(p22) (case 1) and in a 2-year-old girl with 46,XX,del(...

Sex differences in drug metabolism have been reported in numerous species, including humans. In rats and mice, sex-dependent differences in circulating growth hormone profiles are responsible for the differential expression of multiple sex-dependent isoforms of cytochrome P450, which is the basis for the sexual dimorphism in drug metabolism. In contrast, very little is known about sex differenc...

Infertility has a remarkable global impact affecting approximately about 48 million couples worldwide. One of the most contended concerns in reproductive biology is prospective influence psychological stress on pregnancy rates. Individuals struggling to conceive face stupendous amount emotional turbulence and have greater risk for vulnerability. Both infertility reinforce each other; hence, the...