In this study, the identification of mushrooms by using DNA analysis was investigated. Our analysis of internal transcribed spacer (ITS) regions revealed that a DNA-based method could be applicable for samples that are difficult to distinguish in terms of the morphological characteristics. PCR amplification using templates extracted from cooked samples gave sufficient fragments to analyze the s...

Aim of the present investigation was to develop the Self Microemulsifying Drug Delivery System (SMEDDS) of Furosemide. Furosemide is Class IV molecule according to BCS (Biopharmaceutical Classification System), having low solubility and low permeability. Prepared optimized SMEDDS of Furosemide composed of CAPTEX 500 as oil and Cremophore EL as surfactant in 20:80 ratio. Optimized SMEDDS of Furo...

direct orthogonal signal correction(dosc) and savitzky-golay filters (sgf) were applied as preprocessing methods on the original and first derivative absorbance data. principle component regression (pcr), partial least squares (pls) and iterative target transformation factor analysis (ittfa), were used in spectrophotometric simultaneous determination of heavy divalent metal ions, lead, zinc,mer...

the present article is a review of a palaeobiogeographic analysis of jurassic ostracods from east africa, india and madagascar and includes also some general remarks on palaeobiogeography, biodiversity and ostracod ecology.the palaeobiogeographic study shows the high significance of this microfossil group for the reconstruction of palaeogeographic processes, particularly plate tectonic developm...

Objective(s): In this research, zeolite X and zeolite Y were used as vehicle to prepare intestine targeted oral delivery systems of indomethacin and ibuprofen. Materials and Methods: A soaking procedure was implemented to encapsulate indomethacin or ibuprofen within synthetic zeolites. Gravimetric methods and IR spectra of prepared formulations were used to assess drug loading efficiencies into...

BACKGROUND Bacterial conversion of ginsenosides is crucial for the health-promoting effects of ginsenosides. Previous studies on the biotransformation of ginsenoside Rb1 (Rb1) by gut bacteria have focused on the ginsenoside Rd (Rd) pathway (Rb1 → Rd → ginsenoside F2 (F2) → compound K (Cpd K)). This study aims to examine the gypenoside pathway in human gut bacteria in vitro. METHODS The metabo...

In renal transplantation (RT), the major issue is to maintain immune homeostasis, limiting graft rejection (GR), and promoting transplant tolerance. A total of 70 subjects chronic kidney disease patients on maintenance haemodialysis, opted for RT 20 controls were recruited. The Tregs% (CD4+CD25+), concentration cytokines IL –10 17 measured in pre-and post-transplant at a defined timelines with ...

A simple and efficient three components domino reaction of γ-butyrolactam (2-pyrrolidinone), aromatic aldehyde and substituted thiophenol catalyzed by elemental iodine resulted in the formation of 1-((phenylthio)(phenyl)methyl)pyrrolidin-2-one derivatives. The stability of the synthesized analogues was evaluated in stimulated gastric fluid (SGF) and bovine serum albumin (BSA). In vitro anticanc...

Direct orthogonal signal correction(DOSC) and Savitzky-Golay filters (SGF) were applied as preprocessing methods on the original and first derivative absorbance data. Principle component regression (PCR), partial least squares (PLS) and iterative target transformation factor analysis (ITTFA), were used in spectrophotometric simultaneous determination of heavy divalent metal ions, l...

Crystalline arrays of proteinaceous subunits forming surface layers (S-layers) are now recognized as one of the most common outermost cell envelope components of prokaryotic organisms. The surface layer protein of Lactobacillus acidophilus ATCC4356 is composed of a single species of protein of apparent molecular weight of 43-46 KDa. Considering the Lactobacillus acidophilus ATCC4356 having the ...