Subglottic injury (SGI) is a known complication of prolonged intubation in neonates and infants and can lead to failed extubation. SGI is a spectrum that includes mucosal edema, ulceration, granulation perichondritis, and mature scar formation. Although medical management aimed at treating mucosal edema and extraesophageal reflux is successful in treating a majority of patients, some require su...

BACKGROUND Plasmodium falciparum causes severe clinical manifestations by sequestering parasitized red blood cells (PRBC) in the microvasculature of major organs such as the brain. This sequestration results from PRBC adherence to vascular endothelial cells via erythrocyte membrane protein 1, a variant parasite surface antigen. OBJECTIVE To determine whether P. falciparum multiple genotype in...

The collimation of relativistic jets launched from the vicinity supermassive black holes (SMBHs) at centers active galactic nuclei (AGN) is one key questions to understand nature AGN jets. However, little known about detailed jet structure for like quasars since very high angular resolutions are required resolve these objects. We present long baseline interferometry (VLBI) observations archetyp...

OBJECTIVE AND METHODS To estimate median urinary iodine concentration (UIC), and to correlate it with global nutrition indicators and social gap index (SGI) in 50 elementary state schools from 10 municipalities in the State of Queretaro, Mexico. RESULTS 1,544 students were enrolled and an above of requirements of iodine intake was found (median UIC of 297 µg/L). Iodine status was found as def...

Pim kinases are Ser/Thr kinases with multiple substrates that affect survival pathways. These proteins are overexpressed in acute myeloid leukemia (AML) blasts and we hypothesized that Pim kinase inhibition would affect AML cell survival. Imidazo[1,2-b]pyridazine compound, SGI1776 inhibits Pim-1, Pim-2 and Pim-3, and was evaluated in AML-cell line, -xenograft model, and -primary blasts. Treatme...

In this work we discuss hardware and software aspects of parallel 3-D wavelet/subband decomposition on shared memory MIMD computers. Experimental results are conducted on a SGI POWERChal-lenge GR.

In order to understand star formation it is important to understand the dynamics of atomic and molecular clouds in the interstellar medium (ISM). Nonlinear hydrodynamic flows are a key component to the ISM. One route by which nonlinear flows arise is the onset and evolution of interfacial instabilities. Interfacial instabilities act to modify the interface between gas components at different de...

The current dominant concept for the control of saccadic eye movements by the basal ganglia is that release from tonic GABAergic inhibition by the substantia nigra pars reticulata (SNr) triggers burst firings of intermediate gray layer (SGI) neurons in the superior colliculus (SC) to allow saccade initiation. This hypothesis is based on the assumption that SNr cells inhibit excitatory projectio...