Background: The fruit juice of Syzygium alternifolium is used to cure stomach ache and ulcers, while fruit pulp and alcoholic extract of seeds posses anti-diabetic properties. The leaves of plants are claimed for anti-ulcer properties by folklore medicine. Objective: To investigate the antiulcer activity of Ethanolic extract of Syzygium alternifolium (EESA) leaves by Pylorus ligation (Shay rat ...

A shared reality challenges students' ability to deal with threat and crisis. It requires several resources in terms of money and time, as students need a great deal of support, a containing environment, and a relevant knowledge base to establish effective helping relationships. We found a large gap between the design and implementation of the course, introducing modifications to provide the st...

This thesis presents time-optimal self-stabilizing algorithms for distributed spanning tree computation in asynchronous networks. We present both a randomized algorithm for anonymous networks as well as a deterministic version for ID-based networks. Our protocols are the rst to be time-optimal (i.e. stabilize in time O(diameter)) without any prior knowledge of the network size or diameter. Both...

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hTERT-immortalized BS fibroblasts GM03509 (referred as BS) and chromosome 15 minichromosome-corrected BS fibroblasts (referred as A-15) (donated by Jerry Shay), GFP-BLM expressing BS fibroblasts GM08505 (referred as GFP-BLM) (donated by Nathan Ellis) were maintained with DMEM supplemented with 10% FCS, glutamine, sodium pyruvate and antibiotics. hTERT-immortalised RIDDLE patient cell line expre...

The older workers claimed that the gastric secretion of acid was diminished in diabetes mellitus but more recent investigators have found conflicting results. Marks, Shuman, and Shay (1959), using Kay's augmented histamine test, found an acid secretory output in diabetics which differed little from the normal range. In contrast, Dotevall (1961a, b) found that acid output in diabetics was less t...

Telomeres are non-encoding tandem repeats of TTAGGG at the ends of chromosomes. Telomeres are shortened because of incomplete replication at every cell cycle (end replication problem) (Harley et al., 1990) or oxidative damage (von Zglinicki, 2007). Eventual loss of telomeres gives rise to a critical stage of replicative senescence with p53-induced cell cycle arrest. Should this self-regulatory ...

The role of telomeres and telomerase in cancer is an area of much recent interest. This conference sponsored by the American Association of Cancer Research provided a timely opportunity to bring together basic and clinical scientists interested in the field of telomeres and telomerase cancer biology. The meeting included over 250 attendees with 150 oral and poster presentations focused on under...

Cancer-specific TERT promoter mutations (-146C>T and -124C>T) have been linked to reactivation of the epigenetically silenced telomerase reverse transcriptase gene (TERT). Understanding how these single-nucleotide alterations drive TERT reactivation is a fundamental unanswered question and is key for making successful therapeutics. We show that unlike wild-type promoters, recruitment of the tra...

[1] For the Earth magnetotail, the Svenes et al. (2008) statistical study infers the lobe density to be highly variable, in the range of 0.007–0.092 cm . Such lobe density variation modifies reconnection diffusion region physical processes and reconnection rate drastically. This letter addresses observable reconnection signatures in the vicinity of the X-line that are to be affected by the dyna...