Background 31P MRS is an important tool for the measurement of in vivo energetics via the ratio PCr/ATP. Low signal-to-noise (31P molar receptivity is 1/14 that of 1H) coupled with low concentration of high-energy phosphates can result in high measurement variability. 31P MRS of human heart often contains signals originating from blood i.e. 2,3DPG and ATP. Measurement of myocardial PCr/ATP thus...

OBJECTIVE The feasibility of early diagnosis of endometrial carcinoma was studied by least squares support vector machines (LS-SVM) and fuzzy rule-building expert system (FuRES) that classified near infrared (NIR) spectra of tissues. METHODS NIR spectra of 77 specimens of endometrium were collected. The spectra were pretreated by principal component orthogonal signal correction (PC-OSC) and d...

PURPOSE To present a method for spatiotemporal alignment of in-utero magnetic resonance imaging (MRI) time series acquired during maternal hyperoxia for enabling improved quantitative tracking of blood oxygen level-dependent (BOLD) signal changes that characterize oxygen transport through the placenta to fetal organs. MATERIALS AND METHODS The proposed pipeline for spatiotemporal alignment of...

Background As has been shown recently, the use of undersampled 3D projection reconstruction (3DPR) and image-based motion correction with 100% acquisition efficiency [1,2] enables highly accelerated coronary MRA (CMRA) with high isotropic resolution. However, streaking artifact from undersampling significantly reduces the apparent signal-to-noise ratio (SNR). Moreover, affine motion correction ...

Photodiode-array-based spectrometers are increasingly being used in a wide variety of applications. However, the signal measured by this type of instrument often is not what is anticipated by the user and is often subject to contamination from stray light. This paper describes an efficient and low-cost stray light correction approach based on a relatively simple system using a monochromator-bas...

In positron emission tomography, transmission scans are used to correct the acquired data for the effect of photon attenuation. The noise present in the transmission measurement often has a significant effect on the signal to noise ratio of the final attenuation corrected image of the tracer distribution. This study evaluates the effect of different attenuation correction strategies on the perf...

Thank you very much for publishing our manuscript entitled: "Quantification and comparison of bone-specific alkaline phosphatase with two methods in normal and paget's specimens" in the latest issue of the journal (Caspian Journal of Internal Medicine, Summer 2012 3(3):478-483). Unfortunately, we noticed the mistake in the date of our study after its publication in your latest revised manuscrip...

The image quality of a two-photon microscope is often degraded by wavefront aberrations induced by the specimen. We demonstrate here that resolution and signal size in two-photon microcopy can be substantially improved, even in living biological specimens, by adaptive wavefront correction based on sensing the wavefront of coherence-gated backscattered light (coherence-gated wavefront sensing, C...

This paper empirically compares six background correction methods aimed at removing unspecific background noise of the overall signal level measured by a scanner across microarrays. Using three published cDNA microarray datasets we investigated the effect of background correction on cancer classification in terms of the predictive performance of two classifiers (k-NN and support vector machine ...