Diclofenac sodium is a Non-Steroidal Anti-inflammatory Drug, active against relief from pain and inflammation. The main objective of this research work was to prepare Ethyl Cellulose microsphere loaded with Diclofenac and invitro drug release study. In the present study, emulsion Solvent Evaporation Method is used for preparing microsphere. The polymer (EC) and drug (Diclofenac Sodium) was diss...

Hexagonally ordered arrays of polystyrene (PS) microspheres were prepared by a modified air-water self-assembly method. A detailed analysis of the air-water interface self-assembly process was conducted. Several parameters affect the quality of the monolayer colloidal crystals, i.e., the colloidal microsphere concentration on the latex, the surfactant concentration, the polystyrene microsphere ...

The present study assesses effects of acutely infarcted myocardium on apparent microsphere loss as a function of time, determines effects of apparent microsphere loss on blood flow measurements to ischemic regions, and determines to what extent apparent microsphere loss alters interpretation of serial measurements of collateral blood flow. Studies were performed in 35 awake mongrel dogs chronic...

This article introduced the work of ethylcellulose based polymeric microsphere loaded with nifedipine for reduction in frequency of administration with low solubility in aqueous medium and high rate of absorption in the stomach. The non-aqueous polymeric suspension was put dropwise into an aqueous medium containing polyvinyl alcohol as a surfactant for the synthesis of microsphere by solvent ev...

The purpose of this study is to examine the correlation of measured regional cerebral blood flow (rCBF) by means of a new microsphere method (non-invasive microsphere method), to the autoradiography (ARG) method, which is an established quantification method for 123I-IMP brain SPECT. The non-invasive microsphere (NIMS) method and ARG method were simultaneously applied to 30 patients, and quanti...

Quality-factors of waveguide coupled microsphere resonators of 30 μm diameter are measured. A Teflon buffer layer is deposited on the waveguide to separate the microsphere from the waveguide and the effect of this separation on the measured quality-factor is discussed. The whispering-gallery mode propagation along the cavity of the microsphere as well as the optical path lengths of the modes ar...

A lateral dislocation in a double-layer microsphere film is very difficult to identify because the constituent domains have the same two-dimensional crystalline orientation. Orientation-sensitive optical techniques cannot resolve this issue. Here, we demonstrate that partial dark-field (pDF) optical microscopy can be very effective in identifying this type of domain boundary and dislocation of ...

Abstract Mechanochemical reactions at the sliding interface between a single-crystalline silicon (Si) wafer and silica (SiO 2 ) microsphere were studied in three environmental conditions: humid air, potassium chloride (KCl) solution, KCl solution with an applied voltage. Compared to that from mechanochemical material removal surface increased substantially KCl-immersed condition, further when e...

We demonstrate the ability to excite and monitor many whispering gallery modes (WGMs) of a microsphere resonator simultaneously in order to make broadband optical absorbance measurements. The 340 microm diameter microsphere is placed in a microfluidic channel. A hemispherical prism is used for coupling the WGMs into and out of the microsphere. The flat surface of the prism seals the microfluidi...